Recombinant Human MAP3K13 protein is a Human Full Length protein, in the 1 to 966 aa range, expressed in Wheat germ and suitable for ELISA, WB.
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Key facts
- Expression system
- Wheat germ
- Tags
- GST tag N-Terminus
- Applications
- ELISA, WB
- Biologically active
- No
Amino acid sequence
M A N F Q E H L S C S S S P H L P F S E S K T F N G L Q D E L T A M G N H P S P K L L E D Q Q E K G M V R T E L I E S V H S P V T T T V L T S V S E D S R D Q F E N S V L Q L R E H D E S E T A V S Q G N S N T V D G E S T S G T E D I K I Q F S R S G S G S G G F L E G L F G C L R P V W N I I G K A Y S T D Y K L Q Q Q D T W E V P F E E I S E L Q W L G S G A Q G A V F L G K F R A E E V A I K K V R E Q N E T D I K H L R K L K H P N I I A F K G V C T Q A P C Y C I I M E Y C A H G Q L Y E V L R A G R K I T P R L L V D W S T G I A S G M N Y L H L H K I I H R D L K S P N V L V T H T D A V K I S D F G T S K E L S D K S T K M S F A G T V A W M A P E V I R N E P V S E K V D I W S F G V V L W E L L T G E I P Y K D V D S S A I I W G V G S N S L H L P V P S T C P D G F K I L M K Q T W Q S K P R N R P S F R Q T L M H L D I A S A D V L A T P Q E T Y F K S Q A E W R E E V K K H F E K I K S E G T C I H R L D E E L I R R R R E E L R H A L D I R E H Y E R K L E R A N N L Y M E L S A I M L Q L E M R E K E L I K R E Q A V E K K Y P G T Y K R H P V R P I I H P N A M E K L M K R K G V P H K S G M Q T K R P D L L R S E G I P T T E V A P T A S P L S G S P K M S T S S S K S R Y R S K P R H R R G N S R G S H S D F A A I L K N Q P A Q E N S P H P T Y L H Q A Q S Q Y P S L H H H N S L Q Q Q Y Q Q P P P A M S Q S H H P R L N M H G Q D I A T C A N N L R Y F G P A A A L R S P L S N H A Q R Q L P G S S P D L I S T A M A A D C W R S S E P D K G Q A G P W G C C Q A D A Y D P C L Q C R P E Q Y G S L D I P S A E P V G R S P D L S K S P A H N P L L E N A Q S S E K T E E N E F S G C R S E S S L G T S H L G T P P A L P R K T R P L Q K S G D D S S E E E E G E V D S E V E F P R R Q R P H R C I S S C Q S Y S T F S S E N F S V S D G E E G N T S D H S N S P D E L A D K L E D R L A E K L D D L L S Q T P E I P I D I S S H S D G L S D K E C A V R R V K T Q M S L G K L C V E E R G Y E N P M Q F E E S D C D S S D G E C S D A T V R T N K H Y S S A T W
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application ELISA | Reactivity Reacts | Dilution info - | Notes - |
Application WB | Reactivity Reacts | Dilution info - | Notes - |
Target data
Function
Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.
Alternative names
LZK, MAP3K13, Mitogen-activated protein kinase kinase kinase 13, Leucine zipper-bearing kinase, Mixed lineage kinase, MLK
Recommended products
Recombinant Human MAP3K13 protein is a Human Full Length protein, in the 1 to 966 aa range, expressed in Wheat germ and suitable for ELISA, WB.
Key facts
- Expression system
- Wheat germ
- Tags
- GST tag N-Terminus
- Applications
- ELISA, WB
- Biologically active
- No
- Accession
- O43283-1
- Animal free
- No
- Species
- Human
- Concentration
- Storage buffer
pH: 8
Constituents: 0.79% Tris HCl, 0.31% Glutathione
Sequence info
Amino acid sequence
- M A N F Q E H L S C S S S P H L P F S E S K T F N G L Q D E L T A M G N H P S P K L L E D Q Q E K G M V R T E L I E S V H S P V T T T V L T S V S E D S R D Q F E N S V L Q L R E H D E S E T A V S Q G N S N T V D G E S T S G T E D I K I Q F S R S G S G S G G F L E G L F G C L R P V W N I I G K A Y S T D Y K L Q Q Q D T W E V P F E E I S E L Q W L G S G A Q G A V F L G K F R A E E V A I K K V R E Q N E T D I K H L R K L K H P N I I A F K G V C T Q A P C Y C I I M E Y C A H G Q L Y E V L R A G R K I T P R L L V D W S T G I A S G M N Y L H L H K I I H R D L K S P N V L V T H T D A V K I S D F G T S K E L S D K S T K M S F A G T V A W M A P E V I R N E P V S E K V D I W S F G V V L W E L L T G E I P Y K D V D S S A I I W G V G S N S L H L P V P S T C P D G F K I L M K Q T W Q S K P R N R P S F R Q T L M H L D I A S A D V L A T P Q E T Y F K S Q A E W R E E V K K H F E K I K S E G T C I H R L D E E L I R R R R E E L R H A L D I R E H Y E R K L E R A N N L Y M E L S A I M L Q L E M R E K E L I K R E Q A V E K K Y P G T Y K R H P V R P I I H P N A M E K L M K R K G V P H K S G M Q T K R P D L L R S E G I P T T E V A P T A S P L S G S P K M S T S S S K S R Y R S K P R H R R G N S R G S H S D F A A I L K N Q P A Q E N S P H P T Y L H Q A Q S Q Y P S L H H H N S L Q Q Q Y Q Q P P P A M S Q S H H P R L N M H G Q D I A T C A N N L R Y F G P A A A L R S P L S N H A Q R Q L P G S S P D L I S T A M A A D C W R S S E P D K G Q A G P W G C C Q A D A Y D P C L Q C R P E Q Y G S L D I P S A E P V G R S P D L S K S P A H N P L L E N A Q S S E K T E E N E F S G C R S E S S L G T S H L G T P P A L P R K T R P L Q K S G D D S S E E E E G E V D S E V E F P R R Q R P H R C I S S C Q S Y S T F S S E N F S V S D G E E G N T S D H S N S P D E L A D K L E D R L A E K L D D L L S Q T P E I P I D I S S H S D G L S D K E C A V R R V K T Q M S L G K L C V E E R G Y E N P M Q F E E S D C D S S D G E C S D A T V R T N K H Y S S A T W
- Accession
- O43283
- Protein length
- Full Length
- Amino acids
- 1 to 966
- Nature
- Recombinant
- Tags
- GST tag N-Terminus
Specifications
- Form
- Liquid
General info
- Function
Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.
- Sequence similarities
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
- Post-translational modifications
Autophosphorylated on serine and threonine residues.
Storage
- Shipped at conditions
- Dry Ice
- Appropriate short-term storage conditions
- -80°C
- Appropriate long-term storage conditions
- -80°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
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Terms & Conditions.
1 product image
SDS-PAGE - Recombinant Human MAP3K13 protein (ab160368)
ab160368 on a 12.5% SDS-PAGE stained with Coomassie Blue.
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Product protocols
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