Recombinant Human MAP3K13 protein (GST tag N-Terminus)
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Recombinant Human MAP3K13 protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 966 aa range, expressed in Wheat germ, suitable for ELISA, WB.
View Alternative Names
LZK, MAP3K13, Mitogen-activated protein kinase kinase kinase 13, Leucine zipper-bearing kinase, Mixed lineage kinase, MLK
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human MAP3K13 protein (GST tag N-Terminus) (AB160368)
ab160368 on a 12.5% SDS-PAGE stained with Coomassie Blue.
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Specifications
Form
Liquid
General info
Function
Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.
Sequence similarities
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Post-translational modifications
Autophosphorylated on serine and threonine residues.
Target data
Product promise
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