Recombinant Human MCCC1 protein
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Recombinant Human MCCC1 protein is a Human Full Length protein, in the 1 to 725 aa range, expressed in Wheat germ, suitable for ELISA, WB.
View Alternative Names
MCCA, MCCC1, MCCase subunit alpha, 3-methylcrotonyl-CoA carboxylase 1, 3-methylcrotonyl-CoA carboxylase biotin-containing subunit, 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human MCCC1 protein (AB163430)
ab163430 on a 12.5% SDS-PAGE stained with Coomassie Blue.
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
MCCC1 operates as a subunit of the larger 3-methylcrotonyl-CoA carboxylase complex a mitochondrial enzyme important to leucine degradation. By facilitating an early step in this amino acid's breakdown it plays a vital part in the metabolic processes that produce energy and carbon skeletons for biosynthetic pathways. MCCC1's activity reflects its responsibility in coordinating with biotin as a cofactor within the complex ensuring effective enzyme performance.
Pathways
MCCC1 participates in the leucine catabolism and branched-chain amino acid degradation pathways. These pathways incorporate proteins such as the HMG-CoA lyase and enoyl-CoA hydratase which work together to complete the degradation of leucine to acetoacetate and other intermediates. MCCC1 ensures the flow of substrate through these pathways creating links among several metabolic processes important for maintaining energy homeostasis and mitochondrial function.
Specifications
Form
Liquid
General info
Function
Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism.
Post-translational modifications
Acetylated.
Subcellular localisation
Mitochondrion matrix
Target data
Complementary Products
Product promise
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