Recombinant Human Milk Fat Globule 1 protein (Tagged) is a Human Full Length protein, in the 24 to 387 aa range, expressed in Escherichia coli, with >90% purity and suitable for SDS-PAGE.
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Key facts
- Purity
- >90% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
Amino acid sequence
L D I C S K N P C H N G G L C E E I S Q E V R G D V F P S Y T C T C L K G Y A G N H C E T K C V E P L G M E N G N I A N S Q I A A S S V R V T F L G L Q H W V P E L A R L N R A G M V N A W T P S S N D D N P W I Q V N L L R R M W V T G V V T Q G A S R L A S H E Y L K A F K V A Y S L N G H E F D F I H D V N K K H K E F V G N W N K N A V H V N L F E T P V E A Q Y V R L Y P T S C H T A C T L R F E L L G C E L N G C A N P L G L K N N S I P D K Q I T A S S S Y K T W G L H L F S W N P S Y A R L D K Q G N F N A W V A G S Y G N D Q W L Q V D L G S S K E V T G I I T Q G A R N F G S V Q F V A S Y K V A Y S N D S A N W T E Y Q D P R T G S S K I F P G N W D N H S H K K N L F E T P I L A R Y V R I L P V A W H N R I A L R L E L L G C
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
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Target data
Function
Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Medin. Main constituent of aortic medial amyloid.
Alternative names
Lactadherin, Breast epithelial antigen BA46, HMFG, MFGM, Milk fat globule-EGF factor 8, SED1, MFG-E8, MFGE8
Recommended products
Recombinant Human Milk Fat Globule 1 protein (Tagged) is a Human Full Length protein, in the 24 to 387 aa range, expressed in Escherichia coli, with >90% purity and suitable for SDS-PAGE.
Key facts
- Purity
- >90% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
- Accession
- Q08431-1
- Animal free
- No
- Species
- Human
- Concentration
- Storage buffer
pH: 7.2 - 7.4
Constituents: Tris buffer, 50% Glycerol (glycerin, glycerine)
Sequence info
Amino acid sequence
- L D I C S K N P C H N G G L C E E I S Q E V R G D V F P S Y T C T C L K G Y A G N H C E T K C V E P L G M E N G N I A N S Q I A A S S V R V T F L G L Q H W V P E L A R L N R A G M V N A W T P S S N D D N P W I Q V N L L R R M W V T G V V T Q G A S R L A S H E Y L K A F K V A Y S L N G H E F D F I H D V N K K H K E F V G N W N K N A V H V N L F E T P V E A Q Y V R L Y P T S C H T A C T L R F E L L G C E L N G C A N P L G L K N N S I P D K Q I T A S S S Y K T W G L H L F S W N P S Y A R L D K Q G N F N A W V A G S Y G N D Q W L Q V D L G S S K E V T G I I T Q G A R N F G S V Q F V A S Y K V A Y S N D S A N W T E Y Q D P R T G S S K I F P G N W D N H S H K K N L F E T P I L A R Y V R I L P V A W H N R I A L R L E L L G C
- Accession
- Q08431
- Protein length
- Full Length
- Predicted molecular weight
- 56.8 kDa
- Amino acids
- 24 to 387
- Nature
- Recombinant
- Tags
- His tag N-Terminus
Specifications
- Form
- Liquid
General info
- Function
Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction.
- Post-translational modifications
Medin has a ragged N-terminus with minor species starting at Pro-264 and Gly-273.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- -20°C
- Appropriate long-term storage conditions
- -20°C
- Storage information
- Avoid freeze / thaw cycle
Product promise
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1 product image
SDS-PAGE - Recombinant Human Milk Fat Globule 1 protein (Tagged) (ab235800)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) analysis with 5% enrichment gel and 15% separation gel of ab235800.
Downloads
Product protocols
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