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AB187410

Recombinant Human MOSPD1 protein (His tag N-Terminus)

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Recombinant Human MOSPD1 protein (His tag N-Terminus) is a Human Fragment protein, in the 1 to 158 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE, Mass Spec.

View Alternative Names

Motile sperm domain-containing protein 1, MOSPD1

2 Images
SDS-PAGE - Recombinant Human MOSPD1 protein (His tag N-Terminus) (AB187410)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human MOSPD1 protein (His tag N-Terminus) (AB187410)

SDS PAGE analysis using 3µg ab187410 stained with coomassie blue

SDS-PAGE - Recombinant Human MOSPD1 protein (His tag N-Terminus) (AB187410)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human MOSPD1 protein (His tag N-Terminus) (AB187410)

15% SDS-PAGE analysis of ab187410 (3μg).

Key facts

Purity

>85% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

Mass Spec, SDS-PAGE

applications

Biologically active

No

Accession

Q9UJG1

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.4 Constituents: PBS, 20% Glycerol (glycerin, glycerine)

storage-buffer

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Primary Antibodies

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Anti-p53 (phospho S376) antibody [EPR17730]

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Western blot - Anti-p53 (phospho S376) antibody [EPR17730] (AB183547)

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Primary Antibodies

AB247721

Anti-SUPT16H antibody [EPR3685] - BSA and Azide free

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Western blot - Anti-SUPT16H antibody [EPR3685] - BSA and Azide free (AB247721)

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Primary Antibodies

AB169773

Anti-SPANXD antibody [EPR8902]

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Western blot - Anti-SPANXD antibody [EPR8902] (AB169773)

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMHQQKRQPELVEGNLPVFVFPTELIFYADDQSTHKQVLTLYNPYEFALKFKVLCTTPNKYVVVDAAGAVKPQCCVDIVIRHRDVRSCHYGVIDKFRLQVSEQSQRKALGRKEVVATLLPSAKEQQKEEEEKRLKEHLTESLFFEQSFQPENRAVSSGP","proteinLength":"Fragment","predictedMolecularWeight":"20.6 kDa","actualMolecularWeight":null,"aminoAcidEnd":158,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q9UJG1","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The MOSPD1 protein also known as Mesoderm/Posterior 1 or Motile Sperm Domain-Containing Protein 1 is a 458 amino acid protein with a mass of approximately 52 kDa. MOSPD1 localizes primarily to the Golgi apparatus and is expressed in a variety of tissues with particularly high expression in the heart skeletal muscle and testis. The protein features an MSP domain characteristic of the protein family involved in cell motility and signaling.
Biological function summary

MOSPD1 plays a role in cell signaling and interaction processes. The protein does not work as a part of a larger complex but associates with membrane structures including the Golgi membranes and other cellular membranes. This location suggests its involvement in vesicle trafficking or signaling pathways that regulate cellular dynamics. Furthermore MOSPD1 influences cytoskeletal organization affecting cell shape and movement.

Pathways

MOSPD1 is involved in the regulation of the actin cytoskeleton and Golgi-mediated trafficking. It interacts with proteins such as F-actin contributing to the dynamics of cell shape and motility. MOSPD1’s function relates to these pathways by ensuring proper cellular trafficking which is pivotal for maintaining cellular architecture and communication.

Research links MOSPD1 to cardiomyopathy and certain cancers. In cardiomyopathy MOSPD1's interaction with cytoskeletal proteins like F-actin affects myocardial cell structure and function. In cancer aberrant regulation of cell motility and signaling pathways involving MOSPD1 could lead to increased tumor invasiveness and metastasis although the exact mechanisms remain under investigation.
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Specifications

Form

Liquid

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General info

Function

Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to-mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation.

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Product protocols

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Target data

Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to-mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation.
See full target information MOSPD1
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Product promise

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