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AB177722

Recombinant Human MRFAP1L1 protein (His tag N-Terminus)

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Recombinant Human MRFAP1L1 protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 127 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE, Mass Spec.

View Alternative Names

PP784, MRFAP1L1, MORF4 family-associated protein 1-like 1

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SDS-PAGE - Recombinant Human MRFAP1L1 protein (His tag N-Terminus) (AB177722)
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Supplier Data

SDS-PAGE - Recombinant Human MRFAP1L1 protein (His tag N-Terminus) (AB177722)

15% SDS PAGE analysis of ab177722 (3 μg).

Key facts

Purity

>95% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

Mass Spec, SDS-PAGE

applications

Biologically active

No

Accession

Q96HT8

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 20% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMRPLDIDEVEAPEEVEVLEPEEDFEQFLLPVINEMREDIASLIREHGRAYLRTRSKLWEMDNMLIQIKTQVEASEESALNHVQHPSGEADERVSELCEKAEEKAKEIAKMAEMLVELVWRIERSESS","proteinLength":"Full Length","predictedMolecularWeight":"17.2 kDa","actualMolecularWeight":null,"aminoAcidEnd":127,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q96HT8","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

MRFAP1L1 also known as MORF4-related gene family-associated protein 1-like 1 functions as a nuclear protein that may have roles in chromatin modification. This protein has a molecular mass of around 32 kDa. Studies show that MRFAP1L1 has expression in various tissues with notable levels in testes and brain suggesting a potential role in reproductive and neurological processes.
Biological function summary

It interacts with proteins involved in chromatin structure regulation. MRFAP1L1 may act as part of the complexes related to chromatin dynamics influencing the accessibility of DNA for transcription and repair. Its involvement indicates that MRFAP1L1 could play a role in cellular proliferation and differentiation.

Pathways

MRFAP1L1 impacts DNA damage repair and gene expression modulations. Its interactions within the chromatin remodeling pathways suggest associations with proteins like MORF4L1 and RB1 essential for cell cycle regulation and response to DNA injury. MRFAP1L1 therefore contributes to maintaining genomic stability and proper cellular function.

Alterations in MRFAP1L1 expression or function have associations with cancer and neurodegenerative conditions. In various cancers disruption in MRFAP1L1 interactions can affect pathways involving RB1 influencing tumor progression. Studies also suggest potential links between MRFAP1L1 dysregulation and neurodegenerative disorders where chromatin modifications and DNA repair processes are impaired.
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Specifications

Form

Liquid

Additional notes

ab177722 was purified using conventional chromatography techniques.

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General info

Sequence similarities

Belongs to the MORF4 family-associated protein family.

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Product protocols

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Target data

See full target information MRFAP1L1
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