JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB187425

Recombinant Human MRPS23 protein (denatured)

Be the first to review this product! Submit a review

|

(0 Publication)

Recombinant Human MRPS23 protein (denatured) is a Human Full Length protein, in the 1 to 190 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE.

View Alternative Names

CGI-138, HSPC329, MRPS23, Small ribosomal subunit protein mS23, MRP-S23, S23mt

1 Images
SDS-PAGE - Recombinant Human MRPS23 protein (denatured) (AB187425)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human MRPS23 protein (denatured) (AB187425)

15% SDS-PAGE analysis of ab187425 (3μg).

Key facts

Purity

>85% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Q9Y3D9

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.4 Constituents: 90% PBS, 10% Glycerol (glycerin, glycerine)

storage-buffer

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
style
left-column
style
left-column

Sequence info

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMAGSRLETVGSIFSRTRDLVRAGVLKEKPLWFDVYDAFPPLREPVFQRPRVRYGKAKAPIQDIWYHEDRIRAKFYSVYGSGQRAFDLFNPNFKSTCQRFVEKYTELQKLGETDEEKLFVETGKALLAEGVILRRVGEARTQHGGSHVSRKSEHLSVRPQTALEENETQKEVPQDQHLEAPADQSKGLLPP","proteinLength":"Full Length","predictedMolecularWeight":"24.21 kDa","actualMolecularWeight":null,"aminoAcidEnd":190,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q9Y3D9","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
style
left-column

Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The mitochondrial ribosomal protein S23 (MRPS23) is a component of the mitochondrial ribosome. This protein often referred to as MRP-S23 or MRPS23 has a molecular mass of approximately 15 kDa. It plays an important role in mitochondrial protein synthesis. MRPS23 is expressed across various tissue types with substantial presence in tissues with high energy demands such as muscle and neurons.
Biological function summary

MRPS23 facilitates mitochondrial translation by contributing to the assembly and function of the small mitochondrial ribosomal subunit part of the 28S complex. It ensures accurate mitochondrial DNA translation a process important for maintaining mitochondrial function by helping in the binding of mRNA and guiding the synthesis of mitochondrial proteins.

Pathways

MRPS23 plays a role within the oxidative phosphorylation pathway a critical energy-generating process in mitochondria. This target interacts along with other mitochondrial ribosomal proteins like MRPS12 to maintain efficient protein synthesis and subsequently support ATP production. This ties MRPS23 closely to cellular respiration a cornerstone pathway of cellular metabolism.

MRPS23 alterations have been linked to disorders related to mitochondrial dysfunction such as Mitochondrial Encephalopathy. These links emphasize the importance of proper mitochondrial protein synthesis. Moreover interactions with proteins like MRPL12 further connect this target to potential regulatory mechanisms within neurodegenerative diseases shedding light on its role in maintaining neuronal health.
style
left-column

Specifications

Form

Liquid

Additional notes

ab187425 is purified using anion-exchange chromatography (DEAE sepharose resin) and gel-filtration chromatography (Sephacryl S-200) with 20 mM Tris pH 7.5, 2 mM EDTA.

style
left-column

General info

Sequence similarities

Belongs to the mitochondrion-specific ribosomal protein mS23 family.

Subcellular localisation

Mitochondrion

style
left-column

Product protocols

style
left-column

Target data

See full target information MRPS23
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com