Recombinant Human MRRF protein (His tag N-Terminus)
Be the first to review this product! Submit a review
|
(0 Publication)
Recombinant Human MRRF protein (His tag N-Terminus) is a Human Full Length protein, in the 56 to 262 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE, Mass Spec.
View Alternative Names
RRF, mtRRF, MRRF
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human MRRF protein (His tag N-Terminus) (AB137141)
15% SDS-PAGE analysis of 3 µg ab137141.
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
MRRF plays a significant role in mitochondrial translation by promoting the release of ribosomes from mRNA enabling further rounds of translation. It functions as part of the mitochondrial translation machinery and is involved in the maintenance of mitochondrial protein synthesis efficiency. The interaction with other mitochondrial translation factors allows MRRF to efficiently mediate the disassembly of post-termination ribosomal complexes.
Pathways
MRRF is critically involved in the mitochondrial translation process a subset of the broader protein synthesis pathway within the cell. It actively participates in the recycling phase of mitochondrial translation ensuring the effective reuse of ribosomal components. MRRF interacts closely with other proteins such as mtEFG1 (Mitochondrial Elongation Factor G1) to facilitate ribosome recycling and promote cellular energy production linking mitochondrial translation to oxidative phosphorylation.
Specifications
Form
Liquid
Additional notes
ab137141 is purified using conventional chromatography techniques.
General info
Function
Responsible for the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis (PubMed : 19716793, PubMed : 33878294). Acts in collaboration with GFM2 (PubMed : 33878294). Promotes mitochondrial ribosome recycling by dissolution of intersubunit contacts (PubMed : 33878294).
Sequence similarities
Belongs to the RRF family.
Subcellular localisation
Mitochondrion
Target data
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com