Recombinant Human MX2 protein (denatured) is a Human Fragment protein, in the 626 to 715 aa range, expressed in Escherichia coli, with >90% purity and suitable for SDS-PAGE.
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Key facts
- Purity
- >90% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
Amino acid sequence
M R G S H H H H H H G M A S M T G G Q Q M G R D L Y D D D D K D R W G S I G I H L N A Y F L E T S K R L A N Q I P F I I Q Y F M L R E N G D S L Q K A M M Q I L Q E K N R Y S W L L Q E Q S E T A T K R R I L K E R I Y R L T Q A R H A L C Q F S S K E I H
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Target data
Function
Interferon-induced dynamin-like GTPase with potent antiviral activity against human immunodeficiency virus type 1 (HIV-1). Acts by targeting the viral capsid and affects the nuclear uptake and/or stability of the HIV-1 replication complex and the subsequent chromosomal integration of the proviral DNA. Exhibits antiviral activity also against simian immunodeficiency virus (SIV-mnd). May play a role in regulating nucleocytoplasmic transport and cell-cycle progression.
Alternative names
Interferon-induced GTP-binding protein Mx2, Interferon-regulated resistance GTP-binding protein MxB, Myxovirus resistance protein 2, p78-related protein, MX2
Recommended products
Recombinant Human MX2 protein (denatured) is a Human Fragment protein, in the 626 to 715 aa range, expressed in Escherichia coli, with >90% purity and suitable for SDS-PAGE.
Key facts
- Purity
- >90% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
- Accession
- P20592-1
- Animal free
- No
- Species
- Human
- Concentration
- Storage buffer
pH: 8
Constituents: 10% Glycerol (glycerin, glycerine), 2.4% Urea, 0.32% Tris HCl
Sequence info
Amino acid sequence
- M R G S H H H H H H G M A S M T G G Q Q M G R D L Y D D D D K D R W G S I G I H L N A Y F L E T S K R L A N Q I P F I I Q Y F M L R E N G D S L Q K A M M Q I L Q E K N R Y S W L L Q E Q S E T A T K R R I L K E R I Y R L T Q A R H A L C Q F S S K E I H
- Accession
- P20592
- Protein length
- Fragment
- Predicted molecular weight
- 14.9 kDa
- Amino acids
- 626 to 715
- Nature
- Recombinant
- Tags
- His tag N-Terminus
Specifications
- Form
- Liquid
General info
- Function
Interferon-induced dynamin-like GTPase with potent antiviral activity against human immunodeficiency virus type 1 (HIV-1). Acts by targeting the viral capsid and affects the nuclear uptake and/or stability of the HIV-1 replication complex and the subsequent chromosomal integration of the proviral DNA. Exhibits antiviral activity also against simian immunodeficiency virus (SIV-mnd). May play a role in regulating nucleocytoplasmic transport and cell-cycle progression.
- Sequence similarities
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
- Subcellular localisation
- Nucleus, Nuclear pore complex
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
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1 product image
SDS-PAGE - Recombinant Human MX2 protein (denatured) (ab177616)
15% SDS-PAGE analysis of ab177616 (3μg)
Downloads
Product protocols
- Visit the general protocols
- Visit troubleshooting
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