Recombinant Human MX2 protein (denatured) (His tag N-Terminus)
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Recombinant Human MX2 protein (denatured) (His tag N-Terminus) is a Human Fragment protein, in the 626 to 715 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE.
View Alternative Names
Interferon-induced GTP-binding protein Mx2, Interferon-regulated resistance GTP-binding protein MxB, Myxovirus resistance protein 2, p78-related protein, MX2
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human MX2 protein (denatured) (His tag N-Terminus) (AB177616)
15% SDS-PAGE analysis of ab177616 (3μg)
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Specifications
Form
Liquid
General info
Function
Interferon-induced dynamin-like GTPase with potent antiviral activity against human immunodeficiency virus type 1 (HIV-1). Acts by targeting the viral capsid and affects the nuclear uptake and/or stability of the HIV-1 replication complex and the subsequent chromosomal integration of the proviral DNA. Exhibits antiviral activity also against simian immunodeficiency virus (SIV-mnd). May play a role in regulating nucleocytoplasmic transport and cell-cycle progression.
Sequence similarities
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
Subcellular localisation
Nucleus
Target data
Product promise
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