Recombinant Human MYBPC3 protein (His tag) is a Human Fragment protein, in the 1 to 328 aa range, expressed in Escherichia coli, with >90% purity and suitable for SDS-PAGE.
>90% SDS-PAGE
Escherichia coli
His tag N-Terminus
SDS-PAGE
No
M P E P G K K P V S A F S K K P R S V E V A A G S P A V F E A E T E R A G V K V R W Q R G G S D I S A S N K Y G L A T E G T R H T L T V R E V G P A D Q G S Y A V I A G S S K V K F D L K V I E A E K A E P M L A P A P A P A E A T G A P G E A P A P A A E L G E S A P S P K G S S S A A L N G P T P G A P D D P I G L F V M R P Q D G E V T V G G S I T F S A R V A G A S L L K P P V V K W F K G K W V D L S S K V G Q H L Q L H D S Y D R A S K V Y L F E L H I T D A Q P A F T G S Y R C E V S T K D K F D C S N F N L T V H E A M G T G D L D L L S A F R R T S L A G G G R R I S D S H E D T G I L D F S S L L K K R D S F R T P R D S K L E A P A E E D V W E I L R Q A
Application | Reactivity | Dilution info | Notes |
---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
Cardiac MyBP-C, MYBPC3
Recombinant Human MYBPC3 protein (His tag) is a Human Fragment protein, in the 1 to 328 aa range, expressed in Escherichia coli, with >90% purity and suitable for SDS-PAGE.
>90% SDS-PAGE
Escherichia coli
His tag N-Terminus
SDS-PAGE
No
No
Human
pH: 7.2 - 7.4
Constituents: Tris buffer, 50% Glycerol (glycerin, glycerine)
M P E P G K K P V S A F S K K P R S V E V A A G S P A V F E A E T E R A G V K V R W Q R G G S D I S A S N K Y G L A T E G T R H T L T V R E V G P A D Q G S Y A V I A G S S K V K F D L K V I E A E K A E P M L A P A P A P A E A T G A P G E A P A P A A E L G E S A P S P K G S S S A A L N G P T P G A P D D P I G L F V M R P Q D G E V T V G G S I T F S A R V A G A S L L K P P V V K W F K G K W V D L S S K V G Q H L Q L H D S Y D R A S K V Y L F E L H I T D A Q P A F T G S Y R C E V S T K D K F D C S N F N L T V H E A M G T G D L D L L S A F R R T S L A G G G R R I S D S H E D T G I L D F S S L L K K R D S F R T P R D S K L E A P A E E D V W E I L R Q A
Fragment
50.8 kDa
1 to 328
Recombinant
His tag N-Terminus
Liquid
Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
Belongs to the immunoglobulin superfamily. MyBP family.
Substrate for phosphorylation by PKA and PKC. Reversible phosphorylation appears to modulate contraction (By similarity).
Blue Ice
-20°C
-20°C
Upon delivery aliquot
Avoid freeze / thaw cycle
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(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) analysis of ab225662 with 5% enrichment gel and 15% separation gel.
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