Recombinant Human NCALD protein
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Recombinant Human NCALD protein is a Human Full Length protein, in the 1 to 193 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.
View Alternative Names
Neurocalcin-delta, NCALD
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human NCALD protein (AB103901)
15% SDS Page analysis of ab103901 (3 μg)
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Neurocalcin Delta modulates signal transduction by affecting the activity of calcium-dependent enzymes and ion channels. It does so by binding calcium ions which causes a conformational change allowing it to interact with its target proteins. While NCALD does not typically form large protein complexes it often interacts with smaller complexes influencing their function. Its regulatory impact on enzymes and ion channels highlights its important role in maintaining cellular functions.
Pathways
NCALD contributes to various neural signaling pathways notably the calcium signaling pathway and the phototransduction pathway. Within the calcium signaling pathway NCALD interacts with proteins such as calmodulin and recoverin which are important for transmitting calcium signals that control numerous cellular processes. In the phototransduction pathway NCALD functions alongside proteins involved in converting light signals into neuronal signals in the retina.
Specifications
Form
Liquid
Additional notes
Purified using anion-exchange chromatography (DEAE sepharose resin) and gel-filtration chromatography (Sephacryl S-200) with 20mM Tris pH 7.5, 2mM EDTA.
General info
Function
May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions.
Sequence similarities
Belongs to the recoverin family.
Target data
Complementary Products
Product promise
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