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Recombinant Human NCS1 protein is a Human Full Length protein, in the 1 to 190 aa range, expressed in Escherichia coli, with >95% purity and suitable for SDS-PAGE, MS.
Alternative names=Neuronal calcium sensor 1, NCS-1, Frequenin homolog, Frequenin-like protein, Frequenin-like ubiquitous protein, FREQ, FLUP, NCS1
- Purity
>95% SDS-PAGE
- Expression system
Escherichia coli
- Tags
His tag N-Terminus
- Applications
SDS-PAGE, MS
- Biologically active
No
- Sequence
M G S S H H H H H H S S G L V P R G S H M G S M G K S N S K L K P E V V E E L T R K T Y F T E K E V Q Q W Y K G F I K D C P S G Q L D A A G F Q K I Y K Q F F P F G D P T K F A T F V F N V F D E N K D G R I E F S E F I Q A L S V T S R G T L D E K L R W A F K L Y D L D N D G Y I T R N E M L D I V D A I Y Q M V G N T V E L P E E E N T P E K R V D R I F A M M D K N A D G K L T L Q E F Q E G S K A D P S I V Q A L S L Y D G L V
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application MS | Reactivity Reacts | Dilution info - | Notes - |
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Recombinant Human NCS1 protein is a Human Full Length protein, in the 1 to 190 aa range, expressed in Escherichia coli, with >95% purity and suitable for SDS-PAGE, MS.
Alternative names=Neuronal calcium sensor 1, NCS-1, Frequenin homolog, Frequenin-like protein, Frequenin-like ubiquitous protein, FREQ, FLUP, NCS1
Key facts
- Purity
>95% SDS-PAGE
- Expression system
Escherichia coli
- Tags
His tag N-Terminus
- Applications
SDS-PAGE, MS
- Biologically active
No
- Predicted molecular weight
24.3 kDa
- Amino acids
1 to 190
- Sequence
M G S S H H H H H H S S G L V P R G S H M G S M G K S N S K L K P E V V E E L T R K T Y F T E K E V Q Q W Y K G F I K D C P S G Q L D A A G F Q K I Y K Q F F P F G D P T K F A T F V F N V F D E N K D G R I E F S E F I Q A L S V T S R G T L D E K L R W A F K L Y D L D N D G Y I T R N E M L D I V D A I Y Q M V G N T V E L P E E E N T P E K R V D R I F A M M D K N A D G K L T L Q E F Q E G S K A D P S I V Q A L S L Y D G L V
- Accession
- P62166-1
- Protein length
Full Length
- Animal free
No
- Nature
Recombinant
- Species
Human
- Concentration
- Storage buffer
pH: 8
Constituents: 30% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol
Specifications
- Form
Liquid
- Additional notes
ab183224 was purified using conventional chromatography techniques.
General info
- Function
Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity). Stimulates PI4KB kinase activity (By similarity). Involved in long-term synaptic plasticity through its interaction with PICK1 (By similarity). May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel (By similarity).
- Sequence similarities
Belongs to the recoverin family.
Storage
- Shipped at conditions
Blue Ice
- Appropriate short-term storage duration
1-2 weeks
- Appropriate short-term storage conditions
+4°C
- Appropriate long-term storage conditions
-20°C
- Aliquoting information
Upon delivery aliquot
- Storage information
Avoid freeze / thaw cycle
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