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AB101947

Recombinant Human NHP2L1 protein

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Recombinant Human NHP2L1 protein is a Human Full Length protein, in the 1 to 128 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE, Mass Spec.

View Alternative Names

NHP2L1, SNU13, NHP2-like protein 1, High mobility group-like nuclear protein 2 homolog 1, OTK27, SNU13 homolog, U4/U6.U5 small nuclear ribonucleoprotein SNU13, U4/U6.U5 tri-snRNP 15.5 kDa protein, hSNU13

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SDS-PAGE - Recombinant Human NHP2L1 protein (AB101947)
  • SDS-PAGE

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SDS-PAGE - Recombinant Human NHP2L1 protein (AB101947)

15% SDS-PAGE analysis of 3μg ab101947.

Key facts

Purity

>95% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE, Mass Spec

applications

Biologically active

No

Accession

P55769

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.5 Constituents: 10% Glycerol (glycerin, glycerine), 0.58% Sodium chloride, 0.316% Tris HCl

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSHMTEADVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANEATKTLNRGISEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRPVIACSVTIKEGSQLKQQIQSIQQSIERLLV","proteinLength":"Full Length","predictedMolecularWeight":"16.7 kDa","actualMolecularWeight":null,"aminoAcidEnd":128,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P55769","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Liquid

Additional notes

ab101947 is purified using conventional chromatography techniques.

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General info

Function

Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed : 34516797). Involved in pre-mRNA splicing as component of the spliceosome (PubMed : 28781166). Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly (PubMed : 10545122, PubMed : 17412961). The protein undergoes a conformational change upon RNA-binding (PubMed : 10545122, PubMed : 17412961, PubMed : 28781166).

Sequence similarities

Belongs to the eukaryotic ribosomal protein eL8 family.

Subcellular localisation

Nucleus

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Product protocols

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Target data

Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed : 34516797). Involved in pre-mRNA splicing as component of the spliceosome (PubMed : 28781166). Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly (PubMed : 10545122, PubMed : 17412961). The protein undergoes a conformational change upon RNA-binding (PubMed : 10545122, PubMed : 17412961, PubMed : 28781166).
See full target information SNU13
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Complementary Products

Primary Antibodies

AB181982

Anti-NHP2L1 antibody [EPR11671]

RabMAb|Recombinant

Western blot - Anti-NHP2L1 antibody [EPR11671] (AB181982)

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