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AB164128

Recombinant Human NKF3 kinase family member/PEAK1 protein

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Recombinant Human NKF3 kinase family member/PEAK1 protein is a Human Fragment protein, in the 1151 to 1250 aa range, expressed in Wheat germ, suitable for ELISA, WB.

View Alternative Names

KIAA2002, PEAK1, Inactive tyrosine-protein kinase PEAK1, Pseudopodium-enriched atypical kinase 1, Sugen kinase 269, Tyrosine-protein kinase SgK269

1 Images
SDS-PAGE - Recombinant Human NKF3 kinase family member/PEAK1 protein (AB164128)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human NKF3 kinase family member/PEAK1 protein (AB164128)

ab164128 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Key facts

Expression system

Wheat germ

Tags

GST tag N-Terminus

Applications

WB, ELISA

applications

Biologically active

No

Accession

Q9H792

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Product details

This product was previously labelled as NKF3 kinase family member.
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Sequence info

[{"sequence":"TPPPLPKKMIIRANTEPISKDLQKSMESSLCVMANPTYDIDPNWDASSAGSSISYELKGLDIESYDSLERPLRKERPVPSAANSISSLTTLSIKDRFSNS","proteinLength":"Fragment","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":1250,"aminoAcidStart":1151,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q9H792","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Liquid

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General info

Function

Probable catalytically inactive kinase. Scaffolding protein that regulates the cytoskeleton to control cell spreading and migration by modulating focal adhesion dynamics (PubMed : 20534451, PubMed : 23105102, PubMed : 35687021). Acts as a scaffold for mediating EGFR signaling (PubMed : 23846654).

Sequence similarities

Belongs to the protein kinase superfamily.

Post-translational modifications

Phosphorylated on tyrosine in a CSK-dependent manner in response to adhesion to fibronectin and to EGF stimulation (PubMed:20534451). Phosphorylation at Tyr-665 by a Src family kinase controls subcellular localization to focal adhesion and focal adhesion dynamics (PubMed:20534451). Phosphorylation at Tyr-1188 is essential for binding to SHC1 (PubMed:23846654). Phosphorylation at Tyr-635 promotes interaction with tensin TNS3 (PubMed:35687021).

Subcellular localisation

Cytoskeleton

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Product protocols

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Target data

Probable catalytically inactive kinase. Scaffolding protein that regulates the cytoskeleton to control cell spreading and migration by modulating focal adhesion dynamics (PubMed : 20534451, PubMed : 23105102, PubMed : 35687021). Acts as a scaffold for mediating EGFR signaling (PubMed : 23846654).
See full target information PEAK1
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