Recombinant Human NSP 5 alpha 3 alpha protein (His tag N-Terminus)
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Recombinant Human NSP 5 alpha 3 alpha protein (His tag N-Terminus) is a Human Fragment protein, in the 458 to 761 aa range, expressed in Escherichia coli, with >80%, suitable for SDS-PAGE, Mass Spec.
View Alternative Names
CYTSB, NSP5, SPECC1, Cytospin-B, Nuclear structure protein 5, Sperm antigen HCMOGT-1, Sperm antigen with calponin homology and coiled-coil domains 1
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human NSP 5 alpha 3 alpha protein (His tag N-Terminus) (AB181917)
15% SDS-PAGE analysis of ab181917 (3μg).
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
The NSP5 alpha 3 alpha protein acts as a pivotal component of the viral replication machinery. It is a critical member of the viral replication complex which consists of non-structural proteins that work together to produce viral RNA. These complexes form in the cytoplasm of infected host cells and coordinate the replication and transcription of the viral genome. The activity of NSP5 alpha 3 alpha protease cleaves the viral polyprotein at specific sites releasing other non-structural proteins that perform various roles in replication.
Pathways
NSP5 alpha 3 alpha protein plays a central role in the viral RNA synthesis pathway. Its proteolytic activity is essential for the maturation of several non-structural proteins that participate in RNA replication and transcription. NSP5 alpha 3 alpha functions closely with NSP12 an important polymerase enzyme within the viral RNA-dependent RNA polymerase complex. Together these proteins ensure continuous and efficient viral RNA synthesis which is important for successful viral propagation within the host.
Specifications
Form
Liquid
Additional notes
ab181917 was purified by using conventional chromatography techniques.
General info
Sequence similarities
Belongs to the cytospin-A family.
Subcellular localisation
Nucleus
Target data
Complementary Products
Product promise
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