Recombinant Human NST protein is a Human Full Length protein, in the 1 to 284 aa range, expressed in Escherichia coli, with >95% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE, HPLC.
M A E S E A E T P S T P G E F E S K Y F E F H G V R L P P F C R G K M E E I A N F P V R P S D V W I V T Y P K S G T S L L Q E V V Y L V S Q G A D P D E I G L M N I D E Q L P V L E Y P Q P G L D I I K E L T S P R L I K S H L P Y R F L P S D L H N G D S K V I Y M A R N P K D L V V S Y Y Q F H R S L R T M S Y R G T F Q E F C R R F M N D K L G Y G S W F E H V Q E F W E H R M D S N V L F L K Y E D M H R D L V T M V E Q L A R F L G V S C D K A Q L E A L T E H C H Q L V D Q C C S A E A L P V G R G R V G L W K D I F T V S M N E K F D L V Y K Q K M G K C D L T F D F Y L
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application HPLC | Reactivity Reacts | Dilution info - | Notes - |
Atypical sulfotransferase family member with very low affinity for 3'-phospho-5'-adenylyl sulfate (PAPS) and very low catalytic activity towards L-triiodothyronine, thyroxine, estrone, p-nitrophenol, 2-naphthylamine, and 2-beta-naphthol. May have a role in the metabolism of drugs and neurotransmitters in the CNS.
SULTX3, SULT4A1, Sulfotransferase 4A1, ST4A1, Brain sulfotransferase-like protein, Nervous system sulfotransferase, hBR-STL, hBR-STL-1, NST
Recombinant Human NST protein is a Human Full Length protein, in the 1 to 284 aa range, expressed in Escherichia coli, with >95% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE, HPLC.
pH: 7.4
Constituents: 100% PBS
ab172827 is greater than 95%, as determined by SEC-HPLC and reducing SDS-PAGE. It is supplied as an 0.2 µM filtered solution.
Atypical sulfotransferase family member with very low affinity for 3'-phospho-5'-adenylyl sulfate (PAPS) and very low catalytic activity towards L-triiodothyronine, thyroxine, estrone, p-nitrophenol, 2-naphthylamine, and 2-beta-naphthol. May have a role in the metabolism of drugs and neurotransmitters in the CNS.
Belongs to the sulfotransferase 1 family.
Previously labelled as SULT4A1.
The NST protein also known popularly as Non-Structural Protein plays an important role in molecular mechanics. It often displays a specific mass which varies depending on its subtype and source within different organisms. NST typically expresses itself in various cell types mainly in those undergoing specific physiological processes or viral replication. Its expression allows it to interact and modulate several cellular activities adapting according to cellular needs and environmental conditions.
NST proteins perform functions that are integral to cellular operations and survival. As components of several complexes they contribute to the modulation of viral replication processes and cellular stress response mechanisms. Within the host cell NST assists in altering cellular machinery to favor viral propagation ensuring efficiency and survival of viral particles. This modulation often includes interference with normal cell signaling pathways giving malignant cells or viruses a survival advantage.
NST proteins interact dynamically with numerous cellular pathways to ensure their effectiveness. They are notably involved in pathways like the viral infection pathway and the stress response pathway. Within these pathways NST proteins often connect with other proteins like polymerases and helicases facilitating the smooth progression of tasks essential for pathogenesis. These interactions highlight the central role NST plays in altering host cellular functions to align with pathogenic needs.
NST relates particularly to viral infections and resultant complications. Diseases such as virus-induced fever and some respiratory disorders have shown an association with NST proteins. In these contexts proteins such as polymerases directly complement the function of NST enhancing pathogenic processes. This association highlights the potential of targeting NST proteins in therapeutic approaches aimed at mitigating the impacts of such infections and aiding in disease management.
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