Recombinant Human OLA1 protein
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Recombinant Human OLA1 protein is a Human Full Length protein, in the 1 to 396 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE, Mass Spec.
View Alternative Names
GTPBP9, PRO2455, PTD004, OLA1, Obg-like ATPase 1, DNA damage-regulated overexpressed in cancer 45, GTP-binding protein 9, DOC45
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human OLA1 protein (AB130062)
15% SDS-PAGE showing ab130062 (3μg).
Reactivity data
Product details
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
This protein regulates cellular processes such as protein synthesis stress response and mitochondrial function. OLA1 acts as a molecular switch influencing the dynamics of the cytoskeleton and protein synthesis machinery. It is an integral part of a multi-protein complex involved in the regulation of translation initiation factor eIF2B suggesting a role in controlling protein production during stress conditions.
Pathways
The actions of OLA1 fit into broader networks controlling cellular stress and protein homeostasis. It plays a significant role in the oxidative stress pathway and impacts the unfolded protein response. OLA1 interacts with other proteins such as HSP70 and eIF2 modulating how cells adapt to the changing environment and ensuring proper protein folding and function. This highlights its integrative role in cellular adaptation mechanisms.
Specifications
Form
Liquid
Additional notes
ab130062 is purified using conventional chromatography techniques.
General info
Function
Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
Sequence similarities
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
Subcellular localisation
Nucleus
Target data
Complementary Products
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
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