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AB276247

Recombinant Human OPCML protein (His tag)

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Recombinant Human OPCML protein (His tag) is a Human Fragment protein, in the 1 to 322 aa range, expressed in HEK 293 cells, with >95%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.

View Alternative Names

IGLON1, OBCAM, OPCML, Opioid-binding protein/cell adhesion molecule, Opioid-binding cell adhesion molecule, IgLON family member 1

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SDS-PAGE - Recombinant Human OPCML protein (His tag) (AB276247)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human OPCML protein (His tag) (AB276247)

SDS-PAGE analysis of ab276247

Key facts

Purity

>95% SDS-PAGE

Endotoxin level

< 1 EU/µg

Expression system

HEK 293 cells

Tags

His tag C-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Q14982

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.4 Constituents: 100% PBS

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPGAVIDGVN","proteinLength":"Fragment","predictedMolecularWeight":"34 kDa","actualMolecularWeight":null,"aminoAcidEnd":322,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"Q14982","tags":[{"tag":"His","terminus":"C-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

OPCML or Opioid-Binding Protein/Cell Adhesion Molecule-Like is a glycoprotein involved in cell adhesion processes. It weighs approximately 38 kDa and is located on the surface of cells within the nervous system and certain epithelial tissues. As a membrane-bound protein OPCML plays a role in modulating the interactions between cells and the extracellular matrix.
Biological function summary

OPCML influences cell signaling and adhesion through its interactions with other cellular proteins. It is not a part of a larger complex but its role in cell adhesion impacts the organization of cells and tissues. OPCML assists in maintaining proper cellular architecture and is essential for normal cellular communication.

Pathways

OPCML participates in pathways that regulate cellular adhesion and migration. It interacts with other proteins such as integrins and plays a role in the focal adhesion pathway. OPCML's involvement in these pathways helps to govern cell movement and positioning ensuring cells remain in their appropriate locations within tissues.

OPCML has connections to various types of cancers including ovarian and breast cancer. Changes in OPCML expression and function can disrupt normal cell adhesion contributing to cancer progression. OPCML's interaction with cadherins another group of adhesion proteins is notable in the context of these diseases as it can influence tumor spread and metastasis.
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Specifications

Form

Lyophilized

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General info

Function

Binds opioids in the presence of acidic lipids; probably involved in cell contact.

Sequence similarities

Belongs to the immunoglobulin superfamily. IgLON family.

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Product protocols

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Target data

Binds opioids in the presence of acidic lipids; probably involved in cell contact.
See full target information OPCML
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Product promise

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