Recombinant Human OR13A1 protein is a Human Full Length protein, in the 1 to 328 aa range, expressed in Cell free, with >=85% purity and suitable for SDS-PAGE.
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Key facts
- Purity
- >=85% SDS-PAGE
- Expression system
- Cell free
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
Amino acid sequence
M K L W M E S H L I V P E T R P S P R M M S N Q T L V T E F I L Q G F S E H P E Y R V F L F S C F L F L Y S G A L T G N V L I T L A I T F N P G L H A P M Y F F L L N L A T M D I I C T S S I M P K A L A S L V S E E S S I S Y G G C M A Q L Y F L T W A A S S E L L L L T V M A Y D R Y A A I C H P L H Y S S M M S K V F C S G L A T A V W L L C A V N T A I H T G L M L R L D F C G P N V I I H F F C E V P P L L L L S C S S T Y V N G V M I V L A D A F Y G I V N F L M T I A S Y G F I V S S I L K V K T A W G R Q K A F S T C S S H L T V V C M Y Y T A V F Y A Y I S P V S G Y S A G K S K L A G L L Y T V L S P T L N P L I Y T L R N K E V K A A L R K L F P F F R N
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Alternative names
Olfactory receptor 13A1, Olfactory receptor OR10-3, OR13A1
Recommended products
Recombinant Human OR13A1 protein is a Human Full Length protein, in the 1 to 328 aa range, expressed in Cell free, with >=85% purity and suitable for SDS-PAGE.
Key facts
- Purity
- >=85% SDS-PAGE
- Expression system
- Cell free
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
- Accession
- Q8NGR1-1
- Animal free
- Yes
- Species
- Human
- Concentration
- Storage buffer
pH: 7.4 - 8
Constituents: 6% Trehalose, 0.87% Sodium chloride, 0.24% Tris, 0.05% 2-Octadecoxyethanol
Sequence info
Amino acid sequence
- M K L W M E S H L I V P E T R P S P R M M S N Q T L V T E F I L Q G F S E H P E Y R V F L F S C F L F L Y S G A L T G N V L I T L A I T F N P G L H A P M Y F F L L N L A T M D I I C T S S I M P K A L A S L V S E E S S I S Y G G C M A Q L Y F L T W A A S S E L L L L T V M A Y D R Y A A I C H P L H Y S S M M S K V F C S G L A T A V W L L C A V N T A I H T G L M L R L D F C G P N V I I H F F C E V P P L L L L S C S S T Y V N G V M I V L A D A F Y G I V N F L M T I A S Y G F I V S S I L K V K T A W G R Q K A F S T C S S H L T V V C M Y Y T A V F Y A Y I S P V S G Y S A G K S K L A G L L Y T V L S P T L N P L I Y T L R N K E V K A A L R K L F P F F R N
- Accession
- Q8NGR1
- Protein length
- Full Length
- Predicted molecular weight
- 39.3 kDa
- Amino acids
- 1 to 328
- Nature
- Recombinant
- Tags
- His tag N-Terminus
Specifications
- Form
- Lyophilized
General info
- Function
Odorant receptor.
- Sequence similarities
Belongs to the G-protein coupled receptor 1 family.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
OR13A1 also known as olfactory receptor 13A1 is a member of the large family of G-protein-coupled receptors (GPCRs). This protein plays an important role in detecting odor molecules as part of the olfactory system. It has a molecular mass of approximately 35 kDa. OR13A1 is expressed in the olfactory epithelium where olfactory receptors are located and is involved in initiating the neuronal responses that result in the perception of smell.
- Biological function summary
OR13A1 participates in the detection and differentiation of odorants acting as a critical mediator in olfactory signal transduction. It functions by binding specific volatile molecules which triggers a conformational change activating an associated G-protein. This receptor does not work alone; it is an integral component of a receptor complex that collaborates in amplifying and processing olfactory signals.
- Pathways
The olfactory receptor OR13A1 is part of the olfactory signaling pathway which is responsible for odor detection and transmission to the brain. This pathway involves the activation of adenylate cyclase through G-proteins leading to the synthesis of cyclic AMP which opens ion channels. This process is shared with other olfactory receptors including related GPCR proteins such as OR1A1 ensuring a consistent mechanism for odor signal transduction.
- Associated diseases and disorders
Alterations or dysfunction in OR13A1 may contribute to anosmia or hyposmia conditions characterized by the loss or reduction in the ability to smell. These conditions can result from genetic mutations or environmental factors affecting OR13A1. OR13A1 through its signaling pathway may also interact with other olfactory proteins like OR13C5 which might be implicated in such olfactory dysfunctions.
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SDS-PAGE - Recombinant Human OR13A1 protein (ab289768)
SDS-PAGE analysis of ab289768
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