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AB289768

Recombinant Human OR13A1 protein

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Recombinant Human OR13A1 protein is a Human Full Length protein, in the 1 to 328 aa range, expressed in Cell free, with >85%, suitable for SDS-PAGE.

View Alternative Names

Olfactory receptor 13A1, Olfactory receptor OR10-3, OR13A1

1 Images
SDS-PAGE - Recombinant Human OR13A1 protein (AB289768)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human OR13A1 protein (AB289768)

SDS-PAGE analysis of ab289768

Key facts

Purity

>85% SDS-PAGE

Expression system

Cell free

Tags

His tag N-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Q8NGR1

Animal free

Yes

Carrier free

No

Species

Human

Storage buffer

pH: 7.4 - 8 Constituents: 6% Trehalose, 0.87% Sodium chloride, 0.24% Tris, 0.05% 2-Octadecoxyethanol

storage-buffer

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

Sequence info

[{"sequence":"MKLWMESHLIVPETRPSPRMMSNQTLVTEFILQGFSEHPEYRVFLFSCFLFLYSGALTGNVLITLAITFNPGLHAPMYFFLLNLATMDIICTSSIMPKALASLVSEESSISYGGCMAQLYFLTWAASSELLLLTVMAYDRYAAICHPLHYSSMMSKVFCSGLATAVWLLCAVNTAIHTGLMLRLDFCGPNVIIHFFCEVPPLLLLSCSSTYVNGVMIVLADAFYGIVNFLMTIASYGFIVSSILKVKTAWGRQKAFSTCSSHLTVVCMYYTAVFYAYISPVSGYSAGKSKLAGLLYTVLSPTLNPLIYTLRNKEVKAALRKLFPFFRN","proteinLength":"Full Length","predictedMolecularWeight":"39.3 kDa","actualMolecularWeight":null,"aminoAcidEnd":328,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Cell free","accessionNumber":"Q8NGR1","tags":[{"tag":"His","terminus":"N-Terminus"}]}]

Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

OR13A1 also known as olfactory receptor 13A1 is a member of the large family of G-protein-coupled receptors (GPCRs). This protein plays an important role in detecting odor molecules as part of the olfactory system. It has a molecular mass of approximately 35 kDa. OR13A1 is expressed in the olfactory epithelium where olfactory receptors are located and is involved in initiating the neuronal responses that result in the perception of smell.
Biological function summary

OR13A1 participates in the detection and differentiation of odorants acting as a critical mediator in olfactory signal transduction. It functions by binding specific volatile molecules which triggers a conformational change activating an associated G-protein. This receptor does not work alone; it is an integral component of a receptor complex that collaborates in amplifying and processing olfactory signals.

Pathways

The olfactory receptor OR13A1 is part of the olfactory signaling pathway which is responsible for odor detection and transmission to the brain. This pathway involves the activation of adenylate cyclase through G-proteins leading to the synthesis of cyclic AMP which opens ion channels. This process is shared with other olfactory receptors including related GPCR proteins such as OR1A1 ensuring a consistent mechanism for odor signal transduction.

Alterations or dysfunction in OR13A1 may contribute to anosmia or hyposmia conditions characterized by the loss or reduction in the ability to smell. These conditions can result from genetic mutations or environmental factors affecting OR13A1. OR13A1 through its signaling pathway may also interact with other olfactory proteins like OR13C5 which might be implicated in such olfactory dysfunctions.

Specifications

Form

Lyophilized

General info

Function

Odorant receptor.

Sequence similarities

Belongs to the G-protein coupled receptor 1 family.

Product protocols

Target data

Odorant receptor.
See full target information OR13A1

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