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Recombinant Human p23 protein is a Human Full Length protein, in the 1 to 160 aa range, expressed in Escherichia coli, with >90% purity and suitable for SDS-PAGE.

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Key facts

Purity

>90%

Expression system

Escherichia coli

Tags

Tag free

Applications

SDS-PAGE

Biologically active

No

Amino acid sequence

S H M Q P A S A K W Y D R R D Y V F I E F C V E D S K D V N V N F E K S K L T F S C L G G S D N F K H L N E I D L F H C I D P N D S K H K R T D R S I L C C L R K G E S G Q S W P R L T K E R A K L N W L S V D F N N W K D W E D D S D E D M S N F D R F S E M M N N M G G D E D V D L P E V D G A D D D S Q D S D D E K M P D L E

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Reactivity data

Application

SDS-PAGE

Reactivity

Reacts

Dilution info

-

Notes

-

Target data

Function

Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes (PubMed:11274138, PubMed:12077419). Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway (PubMed:24711448).

Alternative names

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Recombinant Human p23 protein is a Human Full Length protein, in the 1 to 160 aa range, expressed in Escherichia coli, with >90% purity and suitable for SDS-PAGE.

Alternative names

Key facts

Purity

>90%

Expression system

Escherichia coli

Applications

SDS-PAGE

Accession
Q15185-1
Animal free

No

Species

Human

Concentration
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Storage buffer

Constituents: 10% Glycerol (glycerin, glycerine), 0.48% HEPES, 0.46% Sodium chloride

Sequence info

Amino acid sequence

S H M Q P A S A K W Y D R R D Y V F I E F C V E D S K D V N V N F E K S K L T F S C L G G S D N F K H L N E I D L F H C I D P N D S K H K R T D R S I L C C L R K G E S G Q S W P R L T K E R A K L N W L S V D F N N W K D W E D D S D E D M S N F D R F S E M M N N M G G D E D V D L P E V D G A D D D S Q D S D D E K M P D L E

Accession

Q15185

Protein length

Full Length

Predicted molecular weight

23 kDa

Amino acids

1 to 160

Nature

Recombinant

Specifications

Form

Liquid

General info

Function

Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes (PubMed:11274138, PubMed:12077419). Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway (PubMed:24711448).

Sequence similarities

Belongs to the p23/wos2 family.

Storage

Shipped at conditions

Blue Ice

Appropriate long-term storage conditions

-20°C

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

2 product images

  • SDS-PAGE - Recombinant Human p23 protein (ab256162), expandable thumbnail

    SDS-PAGE - Recombinant Human p23 protein (ab256162)

    SDS-PAGE analysis of ab256162.

  • SDS-PAGE - Recombinant Human p23 protein (ab256162), expandable thumbnail

    SDS-PAGE - Recombinant Human p23 protein (ab256162)

    SDS-PAGE analysis of ab256162.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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