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AB180355

Recombinant Human PAICS/PAIS protein

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Recombinant Human PAICS/PAIS protein is a Human Full Length protein, in the 1 to 425 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.

View Alternative Names

ADE2, AIRC, PAIS, PAICS, Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1 Images
SDS-PAGE - Recombinant Human PAICS/PAIS protein (AB180355)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human PAICS/PAIS protein (AB180355)

15% SDS-PAGE analysis of ab180355 (3 μg).

Key facts

Purity

>90% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE, Mass Spec

applications

Biologically active

No

Accession

P22234

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 20% Glycerol (glycerin, glycerine), 0.58% Sodium chloride, 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Product details

This product was previously labelled as PAICS
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Sequence info

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMATAEVLNIGKKLYEGKTKEVYELLDSPGKVLLQSKDQITAGNAARKNHLEGKAAISNKITSCIFQLLQEAGIKTAFTRKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNPGVKEGYKFYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEILEKSWLPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRDLKEVTPEGLQMVKKNFEWVAERVELLLKSESQCRVVVLMGSTSDLGHCEKIKKACGNFGIPCELRVTSAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVMSGNTAYPVISCPPLTPDWGVQDVWSSLRLPSGLGCSTVLSPEGSAQFAAQIFGLSNHLVWSKLRASILNTWISLKQADKKIRECNL","proteinLength":"Full Length","predictedMolecularWeight":"49.5 kDa","actualMolecularWeight":null,"aminoAcidEnd":425,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P22234","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Liquid

Additional notes

ab180355 was purified using conventional chromatography.

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General info

Function

Bifunctional phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazole succinocarboxamide synthetase catalyzing two reactions of the de novo purine biosynthetic pathway.

Sequence similarities

In the N-terminal section; belongs to the SAICAR synthetase family.. In the C-terminal section; belongs to the AIR carboxylase family. Class II subfamily.

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Product protocols

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Target data

Bifunctional phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazole succinocarboxamide synthetase catalyzing two reactions of the de novo purine biosynthetic pathway.
See full target information PAICS
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Complementary Products

Primary Antibodies

AB224155

Anti-PAICS/PAIS antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PAICS/PAIS antibody (AB224155)

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Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

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Proteins & Peptides

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Recombinant Human STAC protein (denatured)

SDS-PAGE - Recombinant Human STAC protein (denatured) (AB180301)

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Proteins & Peptides

AB180340

Recombinant Human REV1 protein (denatured)

SDS-PAGE - Recombinant Human REV1 protein (denatured) (AB180340)

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Product promise

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