Recombinant human PARP6 protein
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Recombinant human PARP6 protein is a Human Full Length protein, expressed in Baculovirus infected Sf9 cells, with >70%, suitable for SDS-PAGE, FuncS.
View Alternative Names
Protein mono-ADP-ribosyltransferase PARP6, ADP-ribosyltransferase diphtheria toxin-like 17, Poly [ADP-ribose] polymerase 6, ARTD17, PARP-6, PARP6
- FuncS
Unknown
Functional Studies - Recombinant human PARP6 protein (AB79640)
Ribosylation assay - Specific Activity 358 U/mg
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant human PARP6 protein (AB79640)
ab79640 on SDS-PAGE, Molecular Weight 98 kDa
10% SDS-PAGE, Coomassie staining
Lane 1 : ab79640 6µg
Lane 2 : Protein marker
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
PARP6 impacts multiple cellular functions through its enzymatic activity contributing to DNA damage repair and cell cycle regulation. It does not commonly form part of a larger protein complex but it interacts with other proteins to facilitate cell signaling pathways and maintain genomic stability. The enzymatic activity provided by PARP6 supports the modulation of cellular stress responses and maintains the integrity of cellular structures.
Pathways
Researchers have identified PARP6 as a participant in key cellular mechanism pathways including the DNA repair pathway and cell cycle regulation. It has connections with proteins such as PARP1 and PARP2 which collaborate in similar DNA repair mechanisms. PARP6 involves itself in coordinating responses to DNA damage ensuring accurate repair and replication processes that are critical for preventing genome instability.
Specifications
Form
Liquid
Additional notes
Affinity purified.
General info
Function
Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins.
Sequence similarities
Belongs to the ARTD/PARP family.
Post-translational modifications
Auto-mono-ADP-ribosylated.
Target data
Complementary Products
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
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