Recombinant Human PDXP protein (His tag N-Terminus)

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

Pyridoxal phosphate phosphatase affects many cellular processes by maintaining the balance of pyridoxal 5'-phosphate levels. This enzyme is essential for the regulation of processes that depend on pyridoxal phosphate as a cofactor including amino acid metabolism neurotransmitter synthesis and lipid metabolism. It functions independently rather than being part of a large protein complex allowing its activity to directly influence the availability of pyridoxal phosphate for biochemical reactions.

Pathways

The role of pyridoxal phosphate phosphatase spans significant metabolic pathways such as the amino acid catabolic pathway. Here it functions alongside enzymes that require pyridoxal 5'-phosphate for activity including transaminases and decarboxylases. Additionally PDXP interacts with proteins like pyridoxal kinase which phosphorylates pyridoxal to replenish PLP maintaining the balance between synthesis and degradation in the metabolic flux.