Recombinant Human PGM1 protein (His tag N-Terminus)

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

PGM1 contributes significantly to both energy homeostasis and carbohydrate metabolism. It functions as part of a dynamic complex involving other enzymes that manage intracellular energy balance. PGM1 supports glycogen synthesis and breakdown by regulating the availability of glucose-1-phosphate. This dual role makes PGM1 an important protein for maintaining normal metabolic function. Its activity impacts cellular energy levels which is vital for muscle contraction and overall energy distribution in tissues.

Pathways

PGM1 is critically involved in carbohydrate metabolic pathways specifically glycolysis and gluconeogenesis. In glycolysis it participates in converting glucose for energy production. In gluconeogenesis it assists in the generation of glucose from non-carbohydrate substrates. PGM1 interacts closely with other enzymes in these pathways such as glucose-6-phosphate dehydrogenase ensuring efficient energy regulation and metabolic flow within the cell.