Recombinant Human PLC-delta-3 protein
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Recombinant Human PLC-delta-3 protein is a Human Fragment protein, in the 514 to 613 aa range, expressed in Wheat germ, suitable for ELISA, WB.
View Alternative Names
KIAA1964, PLCD3, Phosphoinositide phospholipase C-delta-3, Phospholipase C-delta-3, PLC-delta-3
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human PLC-delta-3 protein (AB164992)
ab164992 on a 12.5% SDS-PAGE stained with Coomassie Blue.
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Specifications
Form
Liquid
General info
Function
Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Essential for trophoblast and placental development. May participate in cytokinesis by hydrolyzing PIP2 at the cleavage furrow (PubMed : 10336610). Regulates neurite outgrowth through the inhibition of RhoA/Rho kinase signaling (By similarity).
Target data
Product promise
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