Recombinant human PLGF protein (Active)
- Bioactive
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(1 Publication)
Recombinant human PLGF protein (Active) is a Human Full Length protein, in the 19 to 170 aa range, expressed in HEK 293 cells, with >95%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE, FuncS.
View Alternative Names
PGFL, PLGF, PGF, Placenta growth factor, PlGF
- FuncS
Supplier Data
Functional Studies - Recombinant human PLGF protein (Active) (AB174025)
Immobilized Rhesus macaque VEGF R1, Mouse IgG2a Fc Tag, low endotoxin at 5 μg/mL (100 μL/well) can bind ab174025 with a linear range of 5-40 ng/mL
- FuncS
Supplier Data
Functional Studies - Recombinant human PLGF protein (Active) (AB174025)
Immobilized ab174025 at 1 μg/mL (100 μL/well) can bind Biotinylated Human VEGF R1, His,Avitag (ab246160) with a linear range of 2-20 ng/mL
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant human PLGF protein (Active) (AB174025)
SDS-PAGE analysis of reduced ab174025 stained overnight with Coomassie Blue.
DTT-reduced Protein migrates as 28-33 kDa due to glycosylation.
Reactivity data
Product details
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Specifications
Form
Lyophilized
General info
Function
Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
Sequence similarities
Belongs to the PDGF/VEGF growth factor family.
Post-translational modifications
N-glycosylated.
Target data
Publications (1)
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Microcirculation (New York, N.Y. : 1994) 21:368-79 PubMed24410720
2014
Applications
Unspecified application
Species
Unspecified reactive species
Product promise
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