Recombinant Human PMM1 protein
Be the first to review this product! Submit a review
|
(0 Publication)
Recombinant Human PMM1 protein is a Human Full Length protein, in the 1 to 262 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.
View Alternative Names
PMMH22, PMM1, Phosphomannomutase 1, PMM 1, PMMH-22
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human PMM1 protein (AB101111)
15% SDS-PAGE analysis of 3μg ab101111.
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
PMM1 facilitates the conversion of mannose phosphates which is important in protein glycosylation pathways particularly in the synthesis of N-linked glycoproteins. PMM1 operates as a monomer and it does not form part of any larger enzymatic complex. Its activity ensures a proper supply of mannose-1-phosphate required for synthesizing GDP-mannose a donor substrate for glycosylation reactions that is critical in the production of structural molecules and signaling pathways.
Pathways
PMM1 plays a significant role in the biosynthesis of GDP-mannose and impacts the N-glycosylation pathway. PMM1's enzymatic activities integrate closely with glycosylation pathways interfacing with proteins involved in glycan assembly and modification. It interacts with other metabolic pathways that involve mannose and cooperatively influences the cellular processes for protein targeting and function through glycosylation alongside proteins like phosphomannose isomerase (PMI).
Specifications
Form
Liquid
Additional notes
ab101111 was purified using conventional chromatography techniques.
General info
Function
Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. In addition, may be responsible for the degradation of glucose-1,6-bisphosphate in ischemic brain.
Sequence similarities
Belongs to the eukaryotic PMM family.
Target data
Complementary Products
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com