Recombinant Human POMC protein is a Human Full Length protein, in the 27 to 267 aa range, expressed in Escherichia coli, with >85% purity and suitable for SDS-PAGE, MS.
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Publications
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- Frontiers in immunology 14:12843012023Paraneoplastic isolated adrenocorticotropic hormone deficiency revealed after immune checkpoint inhibitors therapy: new insights into anti-corticotroph antibody.Applications:Unspecified applicationReactive species:Unspecified reactive speciesShin Urai,Miki Watanabe,Hironori Bando,Yuma Motomura,Masaaki Yamamoto,Motoko Tachihara,Maki Kanzawa,Hidenori Fukuoka,Genzo Iguchi,Wataru OgawaPubMed 38035072
- Nature communications 12:59912021PGRMC1 acts as a size-selective cargo receptor to drive ER-phagic clearance of mutant prohormones.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYu-Jie Chen,Jeffrey Knupp,Anoop Arunagiri,Leena Haataja,Peter Arvan,Billy TsaiPubMed 34645803
- Addiction biology 26:e128562019A history of opioid exposure in females increases the risk of metabolic disorders in their future male offspring.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAnika M Toorie,Fair M Vassoler,Fangfang Qu,Christopher M Schonhoff,Steven Bradburn,Christopher A Murgatroyd,Donna K Slonim,Elizabeth M ByrnesPubMed 31782234
- PloS one 8:e560582013Characterising the mechanism of airway smooth muscle β2 adrenoceptor desensitization by rhinovirus infected bronchial epithelial cells.Applications:Unspecified applicationReactive species:Unspecified reactive speciesDavid Van Ly,Alen Faiz,Christine Jenkins,Ben Crossett,Judith L Black,Brent McParland,Janette K Burgess,Brian G G OliverPubMed 23457497
Key facts
- Purity
- >85% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE, MS
- Biologically active
- No
Amino acid sequence
M G S S H H H H H H S S G L V P R G S H M W C L E S S Q C Q D L T T E S N L L E C I R A C K P D L S A E T P M F P G N G D E Q P L T E N P R K Y V M G H F R W D R F G R R N S S S S G S S G A G Q K R E D V S A G E D C G P L P E G G P E P R S D G A K P G P R E G K R S Y S M E H F R W G K P V G K K R R P V K V Y P N G A E D E S A E A F P L E F K R E L T G Q R L R E G D G P D G P A D D G A G A Q A D L E H S L L V A A E K K D E G P Y R M E H F R W G S P P K D K R Y G G F M T S E K S Q T P L V T L F K N A I I K N A Y K K G E
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application MS | Reactivity Reacts | Dilution info - | Notes - |
Target data
Function
Corticotropin. Stimulates the adrenal glands to release cortisol. Melanocyte-stimulating hormone alpha. Anorexigenic peptide. Increases the pigmentation of skin by increasing melanin production in melanocytes. Melanocyte-stimulating hormone beta. Increases the pigmentation of skin by increasing melanin production in melanocytes. Beta-endorphin. Endogenous orexigenic opiate. Met-enkephalin. Endogenous opiate.
Alternative names
Pro-opiomelanocortin, POMC, Corticotropin-lipotropin
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Recombinant Human POMC protein is a Human Full Length protein, in the 27 to 267 aa range, expressed in Escherichia coli, with >85% purity and suitable for SDS-PAGE, MS.
Key facts
- Purity
- >85% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE, MS
- Biologically active
- No
- Accession
- P01189-1
- Animal free
- No
- Species
- Human
- Concentration
- Storage buffer
pH: 8.5
Constituents: 50% Glycerol (glycerin, glycerine), 1.16% Sodium chloride, 0.316% Tris HCl, 0.0154% (R*,R*)-1,4-Dimercaptobutan-2,3-diol
Sequence info
Amino acid sequence
- M G S S H H H H H H S S G L V P R G S H M W C L E S S Q C Q D L T T E S N L L E C I R A C K P D L S A E T P M F P G N G D E Q P L T E N P R K Y V M G H F R W D R F G R R N S S S S G S S G A G Q K R E D V S A G E D C G P L P E G G P E P R S D G A K P G P R E G K R S Y S M E H F R W G K P V G K K R R P V K V Y P N G A E D E S A E A F P L E F K R E L T G Q R L R E G D G P D G P A D D G A G A Q A D L E H S L L V A A E K K D E G P Y R M E H F R W G S P P K D K R Y G G F M T S E K S Q T P L V T L F K N A I I K N A Y K K G E
- Accession
- P01189
- Protein length
- Full Length
- Predicted molecular weight
- 28.9 kDa
- Amino acids
- 27 to 267
- Nature
- Recombinant
- Tags
- His tag N-Terminus
Specifications
- Form
- Liquid
- Additional notes
ab108118 is purified using conventional chromatography techniques.
General info
- Function
Corticotropin
- Sequence similarities
Belongs to the POMC family.
- Post-translational modifications
Specific enzymatic cleavages at paired basic residues yield the different active peptides.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- -20°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
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In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
SDS-PAGE - Recombinant Human POMC protein (ab108118)
15% SDS-PAGE showing ab108118 at approximately 28.9kDa (3μg).
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Product protocols
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