Recombinant Human PP11 protein (GST tag N-Terminus)
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Recombinant Human PP11 protein (GST tag N-Terminus) is a Human Fragment protein, in the 270 to 369 aa range, expressed in Wheat germ, suitable for ELISA, WB.
View Alternative Names
Uridylate-specific endoribonuclease, Placental protein 11, Protein endoU, PP11, ENDOU
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human PP11 protein (GST tag N-Terminus) (AB160260)
ab160260 on a 12.5% SDS-PAGE stained with Coomassie Blue.
Complementary Products
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Specifications
Form
Liquid
General info
Function
Endoribonuclease that cleaves single-stranded RNAs at 5' of uridylates and releases a product with a 2',3'-cyclic phosphate at the 3'-end. The UU and GU sites are more efficiently cleaved than CU and AU sites (PubMed : 18936097). Targets mRNAs to regulate their expression (PubMed : 37803019).
Sequence similarities
Belongs to the ENDOU family.
Post-translational modifications
It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability, thus two alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both.
Target data
Product promise
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