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Recombinant human PPIH protein is a Human Full Length protein, expressed in Escherichia coli, with >95% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE, FuncS.
Alternative names=Peptidyl-prolyl cis-trans isomerase H, PPIase H, Rotamase H, Small nuclear ribonucleoprotein particle-specific cyclophilin H, U-snRNP-associated cyclophilin SnuCyp-20, CypH, USA-CYP, CYPH, CYP20, PPIH
- Purity
>95% SDS-PAGE
- Endotoxin level
< 1 EU/µg
- Expression system
Escherichia coli
- Tags
Tag free
- Applications
SDS-PAGE, FuncS
- Biologically active
Yes
- Sequence
M A V A N S S P V N P V V F F D V S I G G Q E V G R M K I E L F A D V V P K T A E N F R Q F C T G E F R K D G V P I G Y K G S T F H R V I K D F M I Q G G D F V N G D G T G V A S I Y R G P F A D E N F K L R H S A P G L L S M A N S G P S T N G C Q F F I T C S K C D W L D G K H V V F G K I I D G L L V M R K I E N V P T G P N N K P K L P V V I S Q C G E M
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application FuncS | Reactivity Reacts | Dilution info - | Notes - |
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Recombinant human PPIH protein is a Human Full Length protein, expressed in Escherichia coli, with >95% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE, FuncS.
Alternative names=Peptidyl-prolyl cis-trans isomerase H, PPIase H, Rotamase H, Small nuclear ribonucleoprotein particle-specific cyclophilin H, U-snRNP-associated cyclophilin SnuCyp-20, CypH, USA-CYP, CYPH, CYP20, PPIH
Key facts
- Purity
>95% SDS-PAGE
- Endotoxin level
< 1 EU/µg
- Expression system
Escherichia coli
- Tags
Tag free
- Applications
SDS-PAGE, FuncS
- Biologically active
Yes
- Biological activity
Specific activity is > 220nmol/min/mg, and is defined as the amount of enzyme that cleaves 1umole of suc-AAPF-pNA per minute at 37°C in Tris-Hcl pH8.0 using chymotrypsin.
- Sequence
M A V A N S S P V N P V V F F D V S I G G Q E V G R M K I E L F A D V V P K T A E N F R Q F C T G E F R K D G V P I G Y K G S T F H R V I K D F M I Q G G D F V N G D G T G V A S I Y R G P F A D E N F K L R H S A P G L L S M A N S G P S T N G C Q F F I T C S K C D W L D G K H V V F G K I I D G L L V M R K I E N V P T G P N N K P K L P V V I S Q C G E M
- Accession
- O43447-1
- Protein length
Full Length
- Animal free
No
- Nature
Recombinant
- Species
Human
- Concentration
- Storage buffer
pH: 7.4
Constituents: PBS, 10% Glycerol (glycerin, glycerine)
Specifications
- Form
Liquid
- Additional notes
ab78874 is purified using conventional chromatography techniques.
General info
- Function
PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding (PubMed:20676357). Participates in pre-mRNA splicing. May play a role in the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. May act as a chaperone.
- Sequence similarities
Belongs to the cyclophilin-type PPIase family. PPIase H subfamily.
- Subcellular localisation
Nucleus speckle
Storage
- Shipped at conditions
Blue Ice
- Appropriate short-term storage duration
1-2 weeks
- Appropriate short-term storage conditions
+4°C
- Appropriate long-term storage conditions
-20°C
- Aliquoting information
Upon delivery aliquot
- Storage information
Avoid freeze / thaw cycle
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Product promise
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