Recombinant Human Procathepsin W protein (denatured)
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Recombinant Human Procathepsin W protein (denatured) is a Human Full Length protein, in the 22 to 376 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE.
View Alternative Names
Cathepsin W, Lymphopain, CTSW
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human Procathepsin W protein (denatured) (AB177671)
15% SDS-PAGE analysis of ab177671 (3μg).
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Procathepsin W acts as part of the immune system's machinery for degrading proteins. Although it is not directly involved in any known complexes it functions within the acidic environment of lysosomes. As a protease Procathepsin W helps break down proteins into smaller peptides or amino acids enabling the immune system to process antigens or eliminate damaged proteins. Its activity in immune cells indicates its relevance to immune responses aiding in cell killing processes.
Pathways
Procathepsin W plays a role in the antigen processing and presentation pathway which is important for immune surveillance. It interacts with other proteins such as major histocompatibility complex (MHC) molecules to present peptides to T cells contributing to the adaptive immune response. The enzyme is also indirectly linked to apoptosis through its participation in protein degradation sharing this pathway with other proteases like caspases that facilitate programmed cell death.
Specifications
Form
Liquid
General info
Function
May have a specific function in the mechanism or regulation of T-cell cytolytic activity.. (Microbial infection) Plays a role during influenza virus infection in lungs cells ex vivo. Acts at the level of virus entering host cytoplasm from late endosome.
Sequence similarities
Belongs to the peptidase C1 family.
Target data
Product promise
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