Recombinant Human Protocadherin 21 protein (GST tag N-Terminus)
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Recombinant Human Protocadherin 21 protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 745 aa range, expressed in Wheat germ, suitable for ELISA, WB.
View Alternative Names
KIAA1775, PCDH21, PRCAD, CDHR1, Cadherin-related family member 1, Photoreceptor cadherin, Protocadherin-21, prCAD
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human Protocadherin 21 protein (GST tag N-Terminus) (AB164895)
ab164895 on a 12.5% SDS-PAGE stained with Coomassie Blue.
Complementary Products
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Protocadherin 21 contributes to the organization and connection of photoreceptors and is an integral component of the photoreceptor sensory cilium complex. This protein plays a role in the development and maintenance of the outer segment discs in photoreceptors which are essential for capturing light and initiating phototransduction. The organization and stability provided by PCDH21 assist in the photoreceptors' effective response to light stimulation emphasizing its importance in normal visual function.
Pathways
Photoreceptor cells rely heavily on the phototransduction cascade to convert light signals into neural signals a process in which Protocadherin 21 plays a supportive role. PCDH21 interacts with other retinal proteins such as rhodopsin which is important for the initiation of this cascade. Additionally links to the Wnt signaling pathway suggest a role in cellular communication and signal transduction highlighting PCDH21's broader interaction within cellular pathways important for proper retinal function.
Specifications
Form
Liquid
General info
Function
Potential calcium-dependent cell-adhesion protein. May be required for the structural integrity of the outer segment (OS) of photoreceptor cells (By similarity).
Post-translational modifications
Undergoes proteolytic cleavage; produces a soluble 95 kDa N-terminal fragment and a 25 kDa cell-associated C-terminal fragment.
Target data
Product promise
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