Recombinant Human PRUNE protein is a Human Full Length protein, in the 1 to 453 aa range, expressed in Wheat germ and suitable for ELISA, WB.
Images
Publications
- International journal of molecular sciences 24:2023Human Prune Regulates the Metabolism of Mammalian Inorganic Polyphosphate and Bioenergetics.Applications:Unspecified applicationReactive species:Unspecified reactive speciesErnest R Scoma,Renata T Da Costa,Ho Hang Leung,Pedro Urquiza,Mariona Guitart-Mampel,Vedangi Hambardikar,Lindsey M Riggs,Ching-On Wong,Maria E SolesioPubMed 37762163
Key facts
- Expression system
Wheat germ
- Tags
GST tag N-Terminus
- Applications
ELISA, WB
- Biologically active
No
Amino acid sequence
M E D Y L Q G C R A A L Q E S R P L H V V L G N E A C D L D S T V S A L A L A F Y L A K T T E A E E V F V P V L N I K R S E L P L R G D I V F F L Q K V H I P E S I L I F R D E I D L H A L Y Q A G Q L T L I L V D H H I L S K S D T A L E E A V A E V L D H R P I E P K H C P P C H V S V E L V G S C A T L V T E R I L Q G A P E I L D R Q T A A L L H G T I I L D C V N M D L K I G K A T P K D S K Y V E K L E A L F P D L P K R N D I F D S L Q K A K F D V S G L T T E Q M L R K D Q K T I Y R Q G V K V A I S A I Y M D L E A F L Q R S N L L A D L H A F C Q A H S Y D V L V A M T I F F N T H N E P V R Q L A I F C P H V A L Q T T I C E V L E R S H S P P L K L T P A S S T H P N L H A Y L Q G N T Q V S R K K L L P L L Q E A L S A Y F D S M K I P S G Q P E T A D V S R E Q V D K E L D R A S N S L I S G L S Q D E E D P P L P P T P M N S L V D E C P L D Q G L P K L S A E A V F E K C S Q I S L S Q S T T A S L S K K
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application ELISA | Reactivity Reacts | Dilution info - | Notes - |
Application WB | Reactivity Reacts | Dilution info - | Notes - |
Target data
Function
Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, migration and differentiation, and acts as a negative regulator of NME1. Plays a role in the regulation of neurogenesis (PubMed:28334956). Involved in the regulation of microtubule polymerization (PubMed:28334956).
Alternative names
Exopolyphosphatase PRUNE1, Drosophila-related expressed sequence 17, HTcD37, Protein prune homolog 1, DRES-17, DRES17, hPrune, PRUNE1, PRUNE
Recommended products
Recombinant Human PRUNE protein is a Human Full Length protein, in the 1 to 453 aa range, expressed in Wheat germ and suitable for ELISA, WB.
Alternative names
Exopolyphosphatase PRUNE1, Drosophila-related expressed sequence 17, HTcD37, Protein prune homolog 1, DRES-17, DRES17, hPrune, PRUNE1, PRUNE
Key facts
- Expression system
Wheat germ
- Tags
GST tag N-Terminus
- Applications
ELISA, WB
- Biologically active
No
- Accession
- Q86TP1-1
- Animal free
No
- Species
Human
- Concentration
- Storage buffer
pH: 8
Constituents: 0.79% Tris HCl, 0.31% Glutathione
Sequence info
Amino acid sequence
M E D Y L Q G C R A A L Q E S R P L H V V L G N E A C D L D S T V S A L A L A F Y L A K T T E A E E V F V P V L N I K R S E L P L R G D I V F F L Q K V H I P E S I L I F R D E I D L H A L Y Q A G Q L T L I L V D H H I L S K S D T A L E E A V A E V L D H R P I E P K H C P P C H V S V E L V G S C A T L V T E R I L Q G A P E I L D R Q T A A L L H G T I I L D C V N M D L K I G K A T P K D S K Y V E K L E A L F P D L P K R N D I F D S L Q K A K F D V S G L T T E Q M L R K D Q K T I Y R Q G V K V A I S A I Y M D L E A F L Q R S N L L A D L H A F C Q A H S Y D V L V A M T I F F N T H N E P V R Q L A I F C P H V A L Q T T I C E V L E R S H S P P L K L T P A S S T H P N L H A Y L Q G N T Q V S R K K L L P L L Q E A L S A Y F D S M K I P S G Q P E T A D V S R E Q V D K E L D R A S N S L I S G L S Q D E E D P P L P P T P M N S L V D E C P L D Q G L P K L S A E A V F E K C S Q I S L S Q S T T A S L S K K
- Accession
- Protein length
Full Length
- Amino acids
1 to 453
- Nature
Recombinant
- Tags
GST tag N-Terminus
Specifications
- Form
Liquid
General info
- Function
Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, migration and differentiation, and acts as a negative regulator of NME1. Plays a role in the regulation of neurogenesis (PubMed:28334956). Involved in the regulation of microtubule polymerization (PubMed:28334956).
- Sequence similarities
Belongs to the PPase class C family. Prune subfamily.
- Subcellular localisation
Nucleus
Storage
- Shipped at conditions
Dry Ice
- Appropriate long-term storage conditions
-80°C
- Aliquoting information
Upon delivery aliquot
- Storage information
Avoid freeze / thaw cycle
Notes
U+00A0;
U+00A0;
Product promise
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
SDS-PAGE - Recombinant Human PRUNE protein (ab153466)
ab153466 on a 12.5% SDS-PAGE stained with Coomassie Blue.
Downloads
Product protocols
- Visit the general protocols
- Visit troubleshooting
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com