Recombinant Human PSG9 protein (GST tag N-Terminus)
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Recombinant Human PSG9 protein (GST tag N-Terminus) is a Human Full Length protein, in the 35 to 426 aa range, expressed in Wheat germ, suitable for SDS-PAGE, ELISA, WB.
View Alternative Names
PSG11, PSG9, Pregnancy-specific beta-1-glycoprotein 9, PS-beta-G-9, PSBG-9, Pregnancy-specific glycoprotein 9, PS34, Pregnancy-specific beta-1 glycoprotein B, Pregnancy-specific beta-1-glycoprotein 11, Pregnancy-specific glycoprotein 7, PS-beta-B, PS-beta-G-11, PSBG-11, Pregnancy-specific glycoprotein 11, PSG7
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human PSG9 protein (GST tag N-Terminus) (AB116750)
12.5% SDS-PAGE analysis of ab116750 at approximately 69.23kDa stained with Coomassie Blue.
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Specifications
Form
Liquid
General info
Function
Binds to the small latent transforming growth factor-beta complex, consisting of the N-terminal TGFB1 latency-associated peptide (LAP) and the mature form of TGFB1, thereby leading to the activation of TGFB1 (PubMed : 27389696). The activation of TGFB1 leads to stimulation of naive CD4(+) T-cells to increase FoxP3 expression and to an increase in the number of FoxP3(+) regulatory T-cells (PubMed : 27389696). Induces the differentiation of a suppressive CD4(+)LAP(+)FoxP3(-) T-cell subset (PubMed : 27389696). Induces the secretion of TGFB1 in macrophages, but not in activated CD4(+) T-cells (PubMed : 27389696). May reduce the expression of several pro-inflammatory cytokines and chemokines by CD4(+) T-cells, including IL2 and IL6 (PubMed : 27389696).
Sequence similarities
Belongs to the immunoglobulin superfamily. CEA family.
Target data
Product promise
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