Recombinant Human PSMA Protein is a Human Fragment protein, in the 44 to 750 aa range, expressed in HEK 293, <= 0.005 EU/µg endotoxin level and suitable for SDS-PAGE, MS, HPLC.
K S S N E A T N I T P K H N M K A F L D E L K A E N I K K F L Y N F T Q I P H L A G T E Q N F Q L A K Q I Q S Q W K E F G L D S V E L A H Y D V L L S Y P N K T H P N Y I S I I N E D G N E I F N T S L F E P P P P G Y E N V S D I V P P F S A F S P Q G M P E G D L V Y V N Y A R T E D F F K L E R D M K I N C S G K I V I A R Y G K V F R G N K V K N A Q L A G A K G V I L Y S D P A D Y F A P G V K S Y P D G W N L P G G G V Q R G N I L N L N G A G D P L T P G Y P A N E Y A Y R R G I A E A V G L P S I P V H P I G Y Y D A Q K L L E K M G G S A P P D S S W R G S L K V P Y N V G P G F T G N F S T Q K V K M H I H S T N E V T R I Y N V I G T L R G A V E P D R Y V I L G G H R D S W V F G G I D P Q S G A A V V H E I V R S F G T L K K E G W R P R R T I L F A S W D A E E F G L L G S T E W A E E N S R L L Q E R G V A Y I N A D S S I E G N Y T L R V D C T P L M Y S L V H N L T K E L K S P D E G F E G K S L Y E S W T K K S P S P E F S G M P R I S K L G S G N D F E V F F Q R L G I A S G R A R Y T K N W E T N K F S G Y P L Y H S V Y E T Y E L V E K F Y D P M F K Y H L T V A Q V R G G M V F E L A N S I V L P F D C R D Y A V V L R K Y A D K I Y S I S M K H P Q E M K T Y S V S F D S L F S A V K N F T E I A S K F S E R L Q D F D K S N P I V L R M M N D Q L M F L E R A F I D P L G L P D R P F Y R H V I Y A P S S H N K Y A G E S F P G I Y D A L F D I E S K V D P S K A W G E V K R Q I Y V A A F T V Q A A A E T L S E V A
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application MS | Reactivity Reacts | Dilution info - | Notes - |
Application HPLC | Reactivity Reacts | Dilution info - | Notes - |
Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression. Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.
FOLH, NAALAD1, PSM, PSMA, GIG27, FOLH1, Glutamate carboxypeptidase 2, Cell growth-inhibiting gene 27 protein, Folate hydrolase 1, Folylpoly-gamma-glutamate carboxypeptidase, Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, N-acetylated-alpha-linked acidic dipeptidase I, Prostate-specific membrane antigen, Pteroylpoly-gamma-glutamate carboxypeptidase, FGCP, GCPII, mGCP, NAALADase I
Recombinant Human PSMA Protein is a Human Fragment protein, in the 44 to 750 aa range, expressed in HEK 293, <= 0.005 EU/µg endotoxin level and suitable for SDS-PAGE, MS, HPLC.
pH: 7.4
Constituents: 10.26% Trehalose, 0.727% Dibasic monohydrogen potassium phosphate, 0.248% Potassium phosphate monobasic
>= 95 % HPLC
Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression.
Belongs to the peptidase M28 family. M28B subfamily.
The first two amino acids at the N-terminus of isoform PSMA' appear to be cleaved by limited proteolysis.
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