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Recombinant Human PSMA protein (Tagged) is a Human Fragment protein, in the 44 to 750 aa range, expressed in HEK 293, with >=90% purity and suitable for SDS-PAGE.

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Images

SDS-PAGE - Recombinant Human PSMA protein (Tagged) (AB271724), expandable thumbnail

Key facts

Purity
>=90% SDS-PAGE
Expression system
HEK 293 cells
Tags
His tag N-Terminus Avi tag N-Terminus
Applications
SDS-PAGE
Biologically active
No

Reactivity data

Application
SDS-PAGE
Reactivity
Reacts
Dilution info
-
Notes

This protein runs at a higher molecular weight due to glycosylation.

Target data

Function

Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression. Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.

Alternative names

Recommended products

Recombinant Human PSMA protein (Tagged) is a Human Fragment protein, in the 44 to 750 aa range, expressed in HEK 293, with >=90% purity and suitable for SDS-PAGE.

Key facts

Purity
>=90% SDS-PAGE
Expression system
HEK 293 cells
Applications
SDS-PAGE
Accession
Q04609-1
Animal free
No
Species
Human
Concentration
Loading...
Storage buffer

pH: 7.4
Constituents: 20% Glycerol (glycerin, glycerine), 0.64% Sodium chloride, 0.13% Sodium phosphate, 0.02% Potassium chloride

Sequence info

Amino acid sequence

Accession
Q04609
Protein length
Fragment
Predicted molecular weight
84 kDa
Amino acids
44 to 750
Nature
Recombinant
Tags
His tag N-Terminus, Avi tag N-Terminus

Specifications

Form
Liquid

General info

Function

Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression.

Sequence similarities

Belongs to the peptidase M28 family. M28B subfamily.

Post-translational modifications

The first two amino acids at the N-terminus of isoform PSMA' appear to be cleaved by limited proteolysis.

Storage

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Storage information
Avoid freeze / thaw cycle

Product promise

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In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

1 product image

  • SDS-PAGE - Recombinant Human PSMA protein (Tagged) (ab271724), expandable thumbnail

    SDS-PAGE - Recombinant Human PSMA protein (Tagged) (ab271724)

    SDS-PAGE analysis of 4 μg ab271724.

    This protein runs at a higher molecular weight due to glycosylation.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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