Recombinant Human PSMA4 protein (His tag N-Terminus)
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Recombinant Human PSMA4 protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 261 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE, Mass Spec.
View Alternative Names
HC9, PSC9, PSMA4, Proteasome subunit alpha type-4, Macropain subunit C9, Multicatalytic endopeptidase complex subunit C9, Proteasome component C9, Proteasome subunit L, Proteasome subunit alpha-3, alpha-3
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human PSMA4 protein (His tag N-Terminus) (AB123216)
15% SDS-PAGE showing ab123216 (3µg).
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Specifications
Form
Liquid
Additional notes
ab123216 is purified using conventional chromatography techniques.
General info
Function
Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
Sequence similarities
Belongs to the peptidase T1A family.
Subcellular localisation
Nucleus
Target data
Product promise
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