Recombinant Human Putative 40S ribosomal protein-like (His tag) is a Human Full Length protein, in the 1 to 176 aa range, expressed in Escherichia coli, with >90% purity and suitable for SDS-PAGE.
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Key facts
- Purity
- >90% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
Amino acid sequence
M L M P K K N R I A I H E L L F K E G V M V A K K D V H M P K H P E L A D K N V P N L H V M K A M Q S L K S R G C V K E Q F A W R H F Y W Y L T N E G S Q Y L R D Y L H L P P E I V P A T L H L P P E I V P A T L H R S R P E T G R P R P K G L E G K R P A R L T R R E A D R D T Y R R C S V P P G A D K K A E A G A G S A T E F Q F R G R C G R G R G Q P P Q
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Target data
Alternative names
RPS10L, RPS10P5, Putative ribosomal protein eS10-like, Putative 40S ribosomal protein S10-like
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Recombinant Human Putative 40S ribosomal protein-like (His tag) is a Human Full Length protein, in the 1 to 176 aa range, expressed in Escherichia coli, with >90% purity and suitable for SDS-PAGE.
Key facts
- Purity
- >90% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
- Accession
- Q9NQ39-1
- Animal free
- No
- Species
- Human
- Concentration
- Storage buffer
pH: 7.2 - 7.4
Constituents: Tris buffer, 50% Glycerol (glycerin, glycerine)
Sequence info
Amino acid sequence
- M L M P K K N R I A I H E L L F K E G V M V A K K D V H M P K H P E L A D K N V P N L H V M K A M Q S L K S R G C V K E Q F A W R H F Y W Y L T N E G S Q Y L R D Y L H L P P E I V P A T L H L P P E I V P A T L H R S R P E T G R P R P K G L E G K R P A R L T R R E A D R D T Y R R C S V P P G A D K K A E A G A G S A T E F Q F R G R C G R G R G Q P P Q
- Accession
- Q9NQ39
- Protein length
- Full Length
- Predicted molecular weight
- 36.1 kDa
- Amino acids
- 1 to 176
- Nature
- Recombinant
- Tags
- His tag N-Terminus
Specifications
- Form
- Liquid
General info
- Sequence similarities
Belongs to the eukaryotic ribosomal protein eS10 family.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- -20°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
The Putative 40S ribosomal protein-like sometimes referred to as RPL40-like functions as a structural component within the ribosomal subunit involved in translation. Its molecular weight is approximately 40 kDa. This protein localizes extensively in the cytoplasm specifically integrating into the small ribosomal subunit. Expression occurs widely across various tissues indicating a general role in protein synthesis.
- Biological function summary
The Putative 40S ribosomal protein-like participates in the formation of the ribosome complex which is important for the translation of mRNA into proteins. As part of the ribosomal machinery this protein plays a role in ensuring the accuracy of translation and the efficient production of polypeptides. The interaction within the ribosome highlights its involvement in maintaining cellular protein homeostasis which is important for cell growth and function.
- Pathways
The Putative 40S ribosomal protein-like integrates into the protein synthesis process contributing to the mTOR signaling pathway. The mTOR pathway regulates cell growth proliferation and survival and the protein's role links to its coordination in translation regulation. It also interacts with various translational factors such as eIF3 and eIF4 promoting efficient ribosomal initiation and elongation during protein synthesis.
- Associated diseases and disorders
Research links abnormal expression of ribosomal proteins including the Putative 40S ribosomal protein-like to certain cancers and hereditary ribosomopathies. Alterations in its expression or function may influence tumorigenesis due to disrupted protein synthesis and cell cycle control. Additionally RPL40-like can interact with other ribosomal proteins like RPL5 and RPL11 which are associated with Diamond-Blackfan anemia a disorder resulting from defective ribosome function.
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1 product image
SDS-PAGE - Recombinant Human Putative 40S ribosomal protein-like (His tag) (ab225984)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) analysis of ab225984 with 5% enrichment gel and 15% separation gel.
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