Recombinant Human RAB3IL1 protein (His tag N-Terminus)
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Recombinant Human RAB3IL1 protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 382 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.
View Alternative Names
Guanine nucleotide exchange factor for Rab-3A, Rab-3A-interacting-like protein 1, Rabin3-like 1, Rab3A-interacting-like protein 1, RAB3IL1
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human RAB3IL1 protein (AB187619)
15% SDS-PAGE analysis of ab187619 (3 μg).
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
RAB3IL1 participates in the regulation of intracellular vesicle transport and secretion processes. It interacts with Rab3 proteins impacting synaptic vesicle cycle and neurotransmitter release. Although not forming a stable complex it temporarily associates with its target Rab proteins during activation. The protein influences cellular secretion linking vesicle transport to signal transduction pathways critical for cellular communication.
Pathways
Vesicle-mediated trafficking and synaptic vesicle cycle are important to understanding RAB3IL1's role. It operates within pathways that regulate neurotransmitter release connecting with proteins like synaptotagmin I and UNC-18. These interactions enable accurate timing and regulation of vesicular transport and fusion highlighting RAB3IL1’s importance in neuronal communication.
Specifications
Form
Liquid
Additional notes
ab187619 was purified using conventional chromatography techniques.
General info
Function
Guanine nucleotide exchange factor (GEF) which may activate RAB3A, a GTPase that regulates synaptic vesicle exocytosis. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May also activate RAB8A and RAB8B.
Sequence similarities
Belongs to the SEC2 family.
Target data
Complementary Products
Product promise
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