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AB276582

Recombinant Human RAMP3 protein (Fc Chimera)

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Recombinant Human RAMP3 protein (Fc Chimera) is a Human Fragment protein, in the 1 to 118 aa range, expressed in HEK 293 cells, with >95%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.

View Alternative Names

Receptor activity-modifying protein 3, Calcitonin-receptor-like receptor activity-modifying protein 3, CRLR activity-modifying protein 3, RAMP3

1 Images
SDS-PAGE - Recombinant Human RAMP3 protein (Fc Chimera) (AB276582)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human RAMP3 protein (Fc Chimera) (AB276582)

SDS-PAGE analysis of ab276582

Key facts

Purity

>95% SDS-PAGE

Endotoxin level

< 1 EU/µg

Expression system

HEK 293 cells

Tags

Fc tag C-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

O60896

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.4 Constituents: 100% PBS

storage-buffer

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Complementary Products

Proteins & Peptides

AB276700

Recombinant Human Calcitonin receptor/CT-R protein (Fc Chimera)

SDS-PAGE - Recombinant Human Calcitonin receptor/CT-R protein (Fc Chimera) (AB276700)

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Primary Antibodies

AB78017

Anti-RAMP3 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RAMP3 antibody (AB78017)

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AB276613

Recombinant Human VPAC2 protein (Fc Chimera)

SDS-PAGE - Recombinant Human VPAC2 protein (Fc Chimera) (AB276613)

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Proteins & Peptides

AB181934

Recombinant Human ZNF32 protein (denatured)

SDS-PAGE - Recombinant Human ZNF32 protein (denatured) (AB181934)

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"METGALRRPQLLPLLLLLCGGCPRAGGCNETGMLERLPLCGKAFADMMGKVDVWKWCNLSEFIVYYESFTNCTEMEANVVGCYWPNPLAQGFITGIHRQFFSNCTVDRVHLEDPPDEV","proteinLength":"Fragment","predictedMolecularWeight":"37.8 kDa","actualMolecularWeight":null,"aminoAcidEnd":118,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"O60896","tags":[{"tag":"Fc","terminus":"C-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Lyophilized

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General info

Function

Accessory protein that interacts with and modulates the function of G-protein coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL), calcitonin receptor (CALCR) and G-protein coupled estrogen receptor 1 (GPER1) (PubMed : 23674134, PubMed : 9620797). Required for the transport of CALCRL and GPER1 receptors to the plasma membrane (PubMed : 23674134, PubMed : 9620797). Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner (PubMed : 23674134). Together with CALCRL, form a receptor complex for adrenomedullin/ADM and intermedin/ADM2 (PubMed : 32296767). Together with CALCR, act as a receptor complex for amylin/IAPP (PubMed : 35324283).

Sequence similarities

Belongs to the RAMP family.

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Product protocols

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Target data

Accessory protein that interacts with and modulates the function of G-protein coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL), calcitonin receptor (CALCR) and G-protein coupled estrogen receptor 1 (GPER1) (PubMed : 23674134, PubMed : 9620797). Required for the transport of CALCRL and GPER1 receptors to the plasma membrane (PubMed : 23674134, PubMed : 9620797). Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner (PubMed : 23674134). Together with CALCRL, form a receptor complex for adrenomedullin/ADM and intermedin/ADM2 (PubMed : 32296767). Together with CALCR, act as a receptor complex for amylin/IAPP (PubMed : 35324283).
See full target information Receptor activity-modifying protein 3
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Product promise

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