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Recombinant Human RANK protein is a Human Fragment protein, in the 29 to 313 aa range, expressed in HEK 293, with >95% purity, < 0.1 EU/µg endotoxin level and suitable for SDS-PAGE, FuncS.

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Key facts

Purity

>95% SDS-PAGE

Endotoxin level

< 0.1 EU/µg

Expression system

HEK 293 cells

Tags

Tag free

Applications

SDS-PAGE, FuncS

Biologically active

No

Reactivity data

Application

SDS-PAGE

Reactivity

Reacts

Dilution info

-

Notes

-

Application

FuncS

Reactivity

Reacts

Dilution info

-

Notes

-

Associated Products

Select an associated product type

2 products for Alternative Product

Target data

Function

Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis (PubMed:9878548). Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2 (By similarity). Involved in the regulation of interactions between T-cells and dendritic cells (By similarity).

Alternative names

Recommended products

Recombinant Human RANK protein is a Human Fragment protein, in the 29 to 313 aa range, expressed in HEK 293, with >95% purity, < 0.1 EU/µg endotoxin level and suitable for SDS-PAGE, FuncS.

Key facts

Purity

>95% SDS-PAGE

Endotoxin level

< 0.1 EU/µg

Expression system

HEK 293 cells

Applications

SDS-PAGE, FuncS

Accession
Q9Y6Q6-1
Animal free

No

Species

Human

Reconstitution

Reconstitute with 50µl sterile water to give a final concentration of 1mg/ml.

Concentration
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Storage buffer

Constituents: PBS

Sequence info

Amino acid sequence

Accession

Q9Y6Q6

Protein length

Fragment

Predicted molecular weight

55 kDa

Amino acids

29 to 313

Nature

Recombinant

Specifications

Form

Lyophilized

General info

Function

Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis (PubMed:9878548). Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2 (By similarity). Involved in the regulation of interactions between T-cells and dendritic cells (By similarity).

Storage

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

Up to 6 months

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Notes

After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions.
Inhibits Human rhsRANKL biological functions. Binds to Human and Mouse RANKL.

Product promise

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Terms & Conditions.

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    Product protocols

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