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Recombinant Human RANK protein is a Human Fragment protein, in the 29 to 313 aa range, expressed in HEK 293, with >95% purity, < 0.1 EU/µg endotoxin level and suitable for SDS-PAGE, FuncS.

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Key facts

Purity
>95% SDS-PAGE
Endotoxin level
< 0.1 EU/µg
Expression system
HEK 293 cells
Tags
Tag free
Applications
SDS-PAGE, FuncS
Biologically active
No

Reactivity data

Application
SDS-PAGE
Reactivity
Reacts
Dilution info
-
Notes

-

Application
FuncS
Reactivity
Reacts
Dilution info
-
Notes

-

Associated Products

Select an associated product type

2 products for Alternative Product

Target data

Function

Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis (PubMed:9878548). Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2 (By similarity). Involved in the regulation of interactions between T-cells and dendritic cells (By similarity).

Alternative names

CD265, RANK, TNFRSF11A, Tumor necrosis factor receptor superfamily member 11A, Osteoclast differentiation factor receptor, Receptor activator of NF-KB, ODFR

Recommended products

Recombinant Human RANK protein is a Human Fragment protein, in the 29 to 313 aa range, expressed in HEK 293, with >95% purity, < 0.1 EU/µg endotoxin level and suitable for SDS-PAGE, FuncS.

Key facts

Purity
>95% SDS-PAGE
Endotoxin level
< 0.1 EU/µg
Expression system
HEK 293 cells
Applications
SDS-PAGE, FuncS
Accession
Q9Y6Q6-1
Animal free
No
Species
Human
Reconstitution
Reconstitute with 50µl sterile water to give a final concentration of 1mg/ml.
Concentration
Loading...
Storage buffer

Constituents: PBS

Sequence info

Amino acid sequence

Accession
Q9Y6Q6
Protein length
Fragment
Predicted molecular weight
55 kDa
Amino acids
29 to 313
Nature
Recombinant

Specifications

Form
Lyophilized

General info

Function

Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis (PubMed:9878548). Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2 (By similarity). Involved in the regulation of interactions between T-cells and dendritic cells (By similarity).

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
Up to 6 months
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C

Notes

After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions.
Inhibits Human rhsRANKL biological functions. Binds to Human and Mouse RANKL.

Product promise

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Terms & Conditions.

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