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Recombinant Human RANK protein (Tagged) is a Human Fragment protein, in the 30 to 212 aa range, expressed in HEK 293, with >=71% purity and suitable for SDS-PAGE.

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Images

SDS-PAGE - Recombinant Human RANK protein (Tagged) (AB271727), expandable thumbnail

Key facts

Purity
>=71% SDS-PAGE
Expression system
HEK 293 cells
Tags
Avi tag C-Terminus Fc tag C-Terminus
Applications
SDS-PAGE
Biologically active
No

Amino acid sequence

I A P P C T S E K H Y E H L G R C C N K C E P G K Y M S S K C T T T S D S V C L P C G P D E Y L D S W N E E D K C L L H K V C D T G K A L V A V V A G N S T T P R R C A C T A G Y H W S Q D C E C C R R N T E C A P G L G A Q H P L Q L N K D T V C K P C L A G Y F S D A F S S T D K C R P W T N C T F L G K R V E H H G T E K S D A V C S S S L P A R K P P N E P H V Y L P

Reactivity data

Application
SDS-PAGE
Reactivity
Reacts
Dilution info
-
Notes

This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Target data

Function

Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis (PubMed:9878548). Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2 (By similarity). Involved in the regulation of interactions between T-cells and dendritic cells (By similarity).

Alternative names

Recommended products

Recombinant Human RANK protein (Tagged) is a Human Fragment protein, in the 30 to 212 aa range, expressed in HEK 293, with >=71% purity and suitable for SDS-PAGE.

Key facts

Purity
>=71% SDS-PAGE
Expression system
HEK 293 cells
Applications
SDS-PAGE
Accession
Q9Y6Q6-1
Animal free
No
Species
Human
Concentration
Loading...
Storage buffer

pH: 7.4
Constituents: 20% Glycerol (glycerin, glycerine), 0.64% Sodium chloride, 0.13% Sodium phosphate, 0.02% Potassium chloride

Sequence info

Amino acid sequence

I A P P C T S E K H Y E H L G R C C N K C E P G K Y M S S K C T T T S D S V C L P C G P D E Y L D S W N E E D K C L L H K V C D T G K A L V A V V A G N S T T P R R C A C T A G Y H W S Q D C E C C R R N T E C A P G L G A Q H P L Q L N K D T V C K P C L A G Y F S D A F S S T D K C R P W T N C T F L G K R V E H H G T E K S D A V C S S S L P A R K P P N E P H V Y L P
Accession
Q9Y6Q6
Protein length
Fragment
Predicted molecular weight
49 kDa
Amino acids
30 to 212
Nature
Recombinant
Tags
Avi tag C-Terminus, Fc tag C-Terminus

Specifications

Form
Liquid

General info

Function

Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis (PubMed:9878548). Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2 (By similarity). Involved in the regulation of interactions between T-cells and dendritic cells (By similarity).

Storage

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Storage information
Avoid freeze / thaw cycle

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

1 product image

  • SDS-PAGE - Recombinant Human RANK protein (Tagged) (ab271727), expandable thumbnail

    SDS-PAGE - Recombinant Human RANK protein (Tagged) (ab271727)

    SDS-PAGE analysis of 2 μg ab271727.

    This protein runs at a higher MW by SDS-PAGE due to glycosylation.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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