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AB156731

Recombinant Human RNase 7 protein

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Recombinant Human RNase 7 protein is a Human Full Length protein, in the 29 to 156 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.

View Alternative Names

UNQ2516/PRO6006, RNASE7, Ribonuclease 7, RNase 7, Skin-derived antimicrobial protein 2, SAP-2

1 Images
SDS-PAGE - Recombinant Human RNase 7 protein (AB156731)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human RNase 7 protein (AB156731)

15% SDS-PAGE analysis of 3µg ab156731.

Key facts

Purity

>90% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE, Mass Spec

applications

Biologically active

No

Accession

Q9H1E1

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 10% Glycerol (glycerin, glycerine), 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Product details

Protein previously labeled as Ribonuclease 7.
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Sequence info

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSKPKGMTSSQWFKIQHMQPSPQACNSAMKNINKHTKRCKDLNTFLHEPFSSVAATCQTPKIACKNGDKNCHQSHGPVSLTMCKLTSGKYPNCRYKEKRQNKSYVVACKPPQKKDSQQFHLVPVHLDRVL","proteinLength":"Full Length","predictedMolecularWeight":"16.9 kDa","actualMolecularWeight":null,"aminoAcidEnd":156,"aminoAcidStart":29,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q9H1E1","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Liquid

Additional notes

ab156731 was purified using conventional chromatography.

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General info

Function

Exhibits a potent RNase activity (PubMed : 12244054, PubMed : 12527768, PubMed : 17150966). Has broad-spectrum antimicrobial activity against many pathogenic microorganisms including uropathogenic E.coli (UPEC), and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium (PubMed : 12244054, PubMed : 12527768, PubMed : 17150966, PubMed : 25075772, PubMed : 33818125). Causes loss of bacterial membrane integrity (PubMed : 17150966). Probably contributes to urinary tract sterility (PubMed : 25075772). Bactericidal activity is independent of RNase activity (PubMed : 17150966).

Sequence similarities

Belongs to the pancreatic ribonuclease family.

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Product protocols

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Target data

Exhibits a potent RNase activity (PubMed : 12244054, PubMed : 12527768, PubMed : 17150966). Has broad-spectrum antimicrobial activity against many pathogenic microorganisms including uropathogenic E.coli (UPEC), and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium (PubMed : 12244054, PubMed : 12527768, PubMed : 17150966, PubMed : 25075772, PubMed : 33818125). Causes loss of bacterial membrane integrity (PubMed : 17150966). Probably contributes to urinary tract sterility (PubMed : 25075772). Bactericidal activity is independent of RNase activity (PubMed : 17150966).
See full target information RNASE7
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