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AB153634

Recombinant Human RNase H1/RNH1 protein (GST tag N-Terminus)

5

(1 Review)

|

(6 Publications)

Recombinant Human RNase H1/RNH1 protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 286 aa range, expressed in Wheat germ, with >80%, suitable for SDS-PAGE, ELISA, WB.

View Alternative Names

RNH1, RNASEH1, Ribonuclease H1, RNase H1, Ribonuclease H type II

1 Images
SDS-PAGE - Recombinant Human RNase H1/RNH1 protein (GST tag N-Terminus) (AB153634)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human RNase H1/RNH1 protein (GST tag N-Terminus) (AB153634)

ab153634 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Key facts

Purity

>80%

Expression system

Wheat germ

Tags

GST tag N-Terminus

Applications

SDS-PAGE, ELISA, WB

applications

Biologically active

No

Accession

O60930

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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Complementary Products

Primary Antibodies

AB229078

Anti-RNase H1/RNH1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNase H1/RNH1 antibody (AB229078)

  • 0
  • 0
Primary Antibodies

AB22758

Anti-Nucleolin antibody

BOND RX™ Validated

Western blot - Anti-Nucleolin antibody (AB22758)

  • 4
  • 8
Primary Antibodies

AB201022

Anti-ATM antibody [EPR20100] - ChIP Grade

RabMAb|Recombinant|KO Validated|20ul selling size

Flow Cytometry (Intracellular) - Anti-ATM antibody [EPR20100] - ChIP Grade (AB201022)

  • 0
  • 0
Primary Antibodies

AB5

Anti-CENPF antibody

Western blot - Anti-CENPF antibody (AB5)

  • 4
  • 7
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Product details

Protein concentration is above or equal to 0.03 mg/ml.

This product was previously labelled as RNase H1

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Sequence info

[{"sequence":"MSWLLFLAHRVALAALPCRRGSRGFGMFYAVRRGRKTGVFLTWNECRAQVDRFPAARFKKFATEDEAWAFVRKSASPEVSEGHENQHGQESEAKASKRLREPLDGDGHESAEPYAKHMKPSVEPAPPVSRDTFSYMGDFVVVYTDGCCSSNGRRRPRAGIGVYWGPGHPLNVGIRLPGRQTNQRAEIHAACKAIEQAKTQNINKLVLYTDSMFTINGITNWVQGWKKNGWKTSAGKEVINKEDFVALERLTQGMDIQWMHVPGHSGFIGNEEADRLAREGAKQSED","proteinLength":"Full Length","predictedMolecularWeight":"58.5 kDa","actualMolecularWeight":null,"aminoAcidEnd":286,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"O60930","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Liquid

Additional notes

Glutathione Sepharose 4 Fast Flow

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General info

Function

Endonuclease that specifically degrades the RNA of RNA-DNA hybrids (PubMed : 10497183). Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II (PubMed : 21700224).

Sequence similarities

Belongs to the RNase H family.

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Product protocols

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Target data

Endonuclease that specifically degrades the RNA of RNA-DNA hybrids (PubMed : 10497183). Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II (PubMed : 21700224).
See full target information RNASEH1
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Publications (6)

Recent publications for all applications. Explore the full list and refine your search

Molecular therapy. Nucleic acids 36:102404 PubMed39759873

2025

Discovery and characterization of stereodefined PMO-gapmers targeting tau.

Applications

Unspecified application

Species

Unspecified reactive species

Kunihiko Kanatsu,Yoshinori Takahashi,Tetsuya Sakaguchi,Dae-Shik Kim,Miki Murota,Mingde Shan,Kazuki Fukami,Wataru Itano,Kenji Kikuta,Hikaru Yoshimura,Toshiki Kurokawa,Yuko Nagayama,Rena Ishikawa,Ryo Dairiki,Zhi Zhou,Kristen Sanders,Jacob Stupalski,So Yasui,Diana Liu,Farid Benayoud,Hui Fang,Enxuan Jing,Makoto Ogo,Francis G Fang,John Wang,Hyeong-Wook Choi

iScience 27:109797 PubMed38993671

2024

Bromodomain protein BRD4 directs mitotic cell division of mouse fibroblasts by inhibiting DNA damage.

Applications

Unspecified application

Species

Unspecified reactive species

Tiyun Wu,Haitong Hou,Anup Dey,Mahesh Bachu,Xiongfong Chen,Jan Wisniewski,Fuki Kudoh,Chao Chen,Sakshi Chauhan,Hua Xiao,Richard Pan,Keiko Ozato

Nature communications 14:8021 PubMed38049398

2023

JUN upregulation drives aberrant transposable element mobilization, associated innate immune response, and impaired neurogenesis in Alzheimer's disease.

Applications

Unspecified application

Species

Unspecified reactive species

Chiara Scopa,Samantha M Barnada,Maria E Cicardi,Mo Singer,Davide Trotti,Marco Trizzino

Nature communications 14:2413 PubMed37105964

2023

Chemical evolution of an autonomous DNAzyme with allele-specific gene silencing activity.

Applications

Unspecified application

Species

Unspecified reactive species

Kim Nguyen,Turnee N Malik,John C Chaput

Organic & biomolecular chemistry 20:8243-8258 PubMed36222332

2022

Synthesis and properties of oligodiaminogalactoses that bind to A-type oligonucleotide duplexes.

Applications

Unspecified application

Species

Unspecified reactive species

Tomomi Shiraishi,Kazuki Sato,Rintaro Iwata Hara,Takeshi Wada

Nature communications 12:1654 PubMed33712600

2021

ADAR1 RNA editing enzyme regulates R-loop formation and genome stability at telomeres in cancer cells.

Applications

Unspecified application

Species

Unspecified reactive species

Yusuke Shiromoto,Masayuki Sakurai,Moeko Minakuchi,Kentaro Ariyoshi,Kazuko Nishikura
View all publications
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Product promise

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