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AB290054

Recombinant Human ROR1 Protein

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Recombinant Human ROR1 Protein is a Human Fragment protein, in the 30 to 406 aa range, expressed in HEK 293 cells, with >95%, <0.005 EU/µg endotoxin level.

View Alternative Names

NTRKR1, ROR1, Inactive tyrosine-protein kinase transmembrane receptor ROR1

3 Images
Mass Spectrometry - Recombinant Human ROR1 Protein (AB290054)
  • Mass Spec

Supplier Data

Mass Spectrometry - Recombinant Human ROR1 Protein (AB290054)

Mass determination by ESI-TOF.

Predicted MW is 42434.71 Da. (+/- 10 Da by ESI-TOF). Observed MW is 42439.50 Da.

SDS-PAGE - Recombinant Human ROR1 Protein (AB290054)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human ROR1 Protein (AB290054)

SDS-PAGE analysis of ab290054

HPLC - Recombinant Human ROR1 Protein (AB290054)
  • HPLC

Supplier Data

HPLC - Recombinant Human ROR1 Protein (AB290054)

HPLC analysis of ab290054

Key facts

Purity

>95% HPLC

Endotoxin level

<0.005 EU/µg

Expression system

HEK 293 cells

Tags

Tag free

Biologically active

No

Accession

Q01973

Animal free

No

Carrier free

No

Species

Human

Reconstitution

Reconstitute in PBS

Storage buffer

pH: 7.4 Constituents: 10.26% Trehalose, 0.727% Dibasic monohydrogen potassium phosphate, 0.248% Potassium phosphate monobasic

storage-buffer

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Complementary Products

Primary Antibodies

AB280197

Anti-ROR1 antibody [EPR24451-141]

20ul selling size|RabMAb|Recombinant

Flow Cytometry (Intracellular) - Anti-ROR1 antibody [EPR24451-141] (AB280197)

  • 0
  • 0
Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Primary Antibodies

AB9485

Anti-GAPDH antibody - Loading Control

BOND RX™ Validated|Lab Essentials

Immunocytochemistry/ Immunofluorescence - Anti-GAPDH antibody - Loading Control (AB9485)

  • 5
  • 88
Assay Kits

AB289641

Human ROR1 ELISA Kit

Recombinant|SimpleStep

Sandwich ELISA - Human ROR1 ELISA Kit (AB289641)

  • 0
  • 0
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Sequence info

[{"sequence":"QETELSVSAELVPTSSWNISSELNKDSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEEDGFCQPYRGIACARFIGNRTVYMESLHMQGEIENQITAAFTMIGTSSHLSDKCSQFAIPSLCHYAFPYCDETSSVPKPRDLCRDECEILENVLCQTEYIFARSNPMILMRLKLPNCEDLPQPESPEAANCIRIGIPMADPINKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEAPWCFTLDENFKSDLCDIPACDSKDSKEKNKMEILY","proteinLength":"Fragment","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":406,"aminoAcidStart":30,"nature":"Recombinant","expressionSystem":null,"accessionNumber":"Q01973","tags":[]}]
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
False
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Specifications

Form

Lyophilized

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General info

Function

Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo (PubMed : 25029443). Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling (PubMed : 25029443, PubMed : 27162350). In inner ear, crucial for spiral ganglion neurons to innervate auditory hair cells (PubMed : 27162350). Via IGFBP5 ligand, forms a complex with ERBB2 to enhance CREB oncogenic signaling (PubMed : 36949068).

Sequence similarities

Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.

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Product protocols

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Target data

Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo (PubMed : 25029443). Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling (PubMed : 25029443, PubMed : 27162350). In inner ear, crucial for spiral ganglion neurons to innervate auditory hair cells (PubMed : 27162350). Via IGFBP5 ligand, forms a complex with ERBB2 to enhance CREB oncogenic signaling (PubMed : 36949068).
See full target information ROR1
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Product promise

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