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AB70614

Recombinant human ROR2 protein

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Recombinant human ROR2 protein is a Human Fragment protein, in the 427 to 943 aa range, expressed in Baculovirus infected Sf9 cells, with >80%, suitable for SDS-PAGE, FuncS.

View Alternative Names

NTRKR2, ROR2, Tyrosine-protein kinase transmembrane receptor ROR2

4 Images
Functional Studies - Recombinant human ROR2 protein (AB70614)
  • FuncS

Unknown

Functional Studies - Recombinant human ROR2 protein (AB70614)

Kinase assay

Functional Studies - Recombinant human ROR2 protein (AB70614)
  • FuncS

Unknown

Functional Studies - Recombinant human ROR2 protein (AB70614)

The specific activity of ROR2 (ab70614) was determined to be 0.2 nmol/min/mg as per activity assay protocol

SDS-PAGE - Recombinant human ROR2 protein (AB70614)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant human ROR2 protein (AB70614)

SDS-PAGE showing ab70614 at approximately 86kDa.

SDS-PAGE - Recombinant human ROR2 protein (AB70614)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant human ROR2 protein (AB70614)

SDS PAGE analysis of ab70614

Key facts

Purity

>80% Densitometry

Expression system

Baculovirus infected Sf9 cells

Tags

GST tag N-Terminus

Applications

FuncS, SDS-PAGE

applications

Biologically active

Yes

Biological activity

Active

Accession

Q01974

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.5 Constituents: 25% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, 0.79% Tris HCl, 0.00385% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.0038% EGTA, 0.00292% EDTA, 0.00174% PMSF

storage-buffer

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Complementary Products

Primary Antibodies

AB218105

Anti-ROR2 antibody [EPR19980]

RabMAb|Recombinant|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ROR2 antibody [EPR19980] (AB218105)

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Recombinant human BMP9 protein (Active)

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AB282385

Recombinant Human EGFR protein

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Assay Kits

AB279909

Phosphotyrosine ROR2 ELISA Kit

Sandwich ELISA - Phosphotyrosine ROR2 ELISA Kit (AB279909)

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  • 0
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p>Kinase assay.</p>" } } }
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Product details

ab64311 (Myelin Basic Protein protein) can be utilized as a substrate for assessing kinase activity
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Sequence info

[{"linker":null,"sequence":"","proteinLength":"Fragment","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":943,"aminoAcidStart":427,"nature":"Recombinant","expressionSystem":null,"accessionNumber":"Q01974","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
True
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Specifications

Form

Liquid

Additional notes

Purity is lot specific. Please contact our technical Support team for details.Affinity purified.

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General info

Function

Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity). Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PubMed : 17717073). In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PubMed : 25029443).

Sequence similarities

Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.

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Product protocols

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Target data

Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity). Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PubMed : 17717073). In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PubMed : 25029443).
See full target information ROR2
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Product promise

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For full details, please see our Terms & Conditions

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