Recombinant Human ROR2 protein (His tag) is a Human Fragment protein, in the 34 to 403 aa range, expressed in HEK 293, with >95% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE.
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Key facts
- Purity
- >95% SDS-PAGE
- Endotoxin level
- < 1 EU/µg
- Expression system
- HEK 293 cells
- Tags
- His tag C-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
Amino acid sequence
E V E V L D P N D P L G P L D G Q D G P I P T L K G Y F L N F L E P V N N I T I V Q G Q T A I L H C K V A G N P P P N V R W L K N D A P V V Q E P R R I I I R K T E Y G S R L R I Q D L D T T D T G Y Y Q C V A T N G M K T I T A T G V L F V R L G P T H S P N H N F Q D D Y H E D G F C Q P Y R G I A C A R F I G N R T I Y V D S L Q M Q G E I E N R I T A A F T M I G T S T H L S D Q C S Q F A I P S F C H F V F P L C D A R S R T P K P R E L C R D E C E V L E S D L C R Q E Y T I A R S N P L I L M R L Q L P K C E A L P M P E S P D A A N C M R I G I P A E R L G R Y H Q C Y N G S G M D Y R G T A S T T K S G H Q C Q P W A L Q H P H S H H L S S T D F P E L G G G H A Y C R N P G G Q M E G P W C F T Q N K N V R M E L C D V P S C S P R D S S K M G
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Associated Products
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Target data
Function
Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity). Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PubMed:17717073). In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443).
Alternative names
NTRKR2, ROR2, Tyrosine-protein kinase transmembrane receptor ROR2
Recommended products
Recombinant Human ROR2 protein (His tag) is a Human Fragment protein, in the 34 to 403 aa range, expressed in HEK 293, with >95% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE.
Key facts
- Purity
- >95% SDS-PAGE
- Endotoxin level
- < 1 EU/µg
- Expression system
- HEK 293 cells
- Tags
- His tag C-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
- Accession
- Q01974-1
- Animal free
- No
- Species
- Human
- Reconstitution
- Reconstitute at 400 µg/mL in water
- Concentration
- Storage buffer
pH: 7.4
Constituents: 95% PBS, 5% Trehalose
Sequence info
Amino acid sequence
- E V E V L D P N D P L G P L D G Q D G P I P T L K G Y F L N F L E P V N N I T I V Q G Q T A I L H C K V A G N P P P N V R W L K N D A P V V Q E P R R I I I R K T E Y G S R L R I Q D L D T T D T G Y Y Q C V A T N G M K T I T A T G V L F V R L G P T H S P N H N F Q D D Y H E D G F C Q P Y R G I A C A R F I G N R T I Y V D S L Q M Q G E I E N R I T A A F T M I G T S T H L S D Q C S Q F A I P S F C H F V F P L C D A R S R T P K P R E L C R D E C E V L E S D L C R Q E Y T I A R S N P L I L M R L Q L P K C E A L P M P E S P D A A N C M R I G I P A E R L G R Y H Q C Y N G S G M D Y R G T A S T T K S G H Q C Q P W A L Q H P H S H H L S S T D F P E L G G G H A Y C R N P G G Q M E G P W C F T Q N K N V R M E L C D V P S C S P R D S S K M G
- Accession
- Q01974
- Protein length
- Fragment
- Predicted molecular weight
- 43.2 kDa
- Amino acids
- 34 to 403
- Nature
- Recombinant
- Tags
- His tag C-Terminus
Specifications
- Form
- Lyophilized
General info
- Function
Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity). Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PubMed:17717073). In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443).
- Sequence similarities
Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- -80°C
- Appropriate long-term storage conditions
- -80°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
Product promise
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2 product images
SDS-PAGE - Recombinant Human ROR2 protein (His tag) (ab221029)
SDS-PAGE analysis of reduced ab221029 stained overnight with Coomassie Blue. The reducing protein migrates as 55 kDa in SDS-PAGE due to glycosylation. The purity of the protein is greater than 95%.
ELISA - Recombinant Human ROR2 protein (His tag) (ab221029)
Immobilized ab221029 at 1 μg/mL (100 μL/well) can bind Anti-ROR2 Antibody, Human IgG1 with a linear range of 0.1-4 ng/mL (QC tested).
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Product protocols
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