Recombinant Human ROR2 protein (Tagged) (Biotin) is a Human Fragment protein, in the 28 to 403 aa range, expressed in HEK 293, with >=90% purity and suitable for SDS-PAGE.
Images
Key facts
- Purity
- >=90% SDS-PAGE
- Expression system
- HEK 293 cells
- Tags
- Avi tag C-Terminus Fc tag C-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
- Conjugation
- Biotin
Amino acid sequence
V S R T S G E V E V L D P N D P L G P L D G Q D G P I P T L K G Y F L N F L E P V N N I T I V Q G Q T A I L H C K V A G N P P P N V R W L K N D A P V V Q E P R R I I I R K T E Y G S R L R I Q D L D T T D T G Y Y Q C V A T N G M K T I T A T G V L F V R L G P T H S P N H N F Q D D Y H E D G F C Q P Y R G I A C A R F I G N R T I Y V D S L Q M Q G E I E N R I T A A F T M I G T S T H L S D Q C S Q F A I P S F C H F V F P L C D A R S R T P K P R E L C R D E C E V L E S D L C R Q E Y T I A R S N P L I L M R L Q L P K C E A L P M P E S P D A A N C M R I G I P A E R L G R Y H Q C Y N G S G M D Y R G T A S T T K S G H Q C Q P W A L Q H P H S H H L S S T D F P E L G G G H A Y C R N P G G Q M E G P W C F T Q N K N V R M E L C D V P S C S P R D S S K M G
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Target data
Function
Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity). Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PubMed:17717073). In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443).
Alternative names
NTRKR2, ROR2, Tyrosine-protein kinase transmembrane receptor ROR2
Recommended products
Recombinant Human ROR2 protein (Tagged) (Biotin) is a Human Fragment protein, in the 28 to 403 aa range, expressed in HEK 293, with >=90% purity and suitable for SDS-PAGE.
Key facts
- Purity
- >=90% SDS-PAGE
- Expression system
- HEK 293 cells
- Tags
- Avi tag C-Terminus Fc tag C-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
- Conjugation
- Biotin
- Accession
- Q01974-1
- Animal free
- No
- Species
- Human
- Concentration
- Storage buffer
pH: 7.4
Constituents: 20% Glycerol (glycerin, glycerine), 0.64% Sodium chloride, 0.13% Sodium phosphate, 0.02% Potassium chloride
Sequence info
Amino acid sequence
- V S R T S G E V E V L D P N D P L G P L D G Q D G P I P T L K G Y F L N F L E P V N N I T I V Q G Q T A I L H C K V A G N P P P N V R W L K N D A P V V Q E P R R I I I R K T E Y G S R L R I Q D L D T T D T G Y Y Q C V A T N G M K T I T A T G V L F V R L G P T H S P N H N F Q D D Y H E D G F C Q P Y R G I A C A R F I G N R T I Y V D S L Q M Q G E I E N R I T A A F T M I G T S T H L S D Q C S Q F A I P S F C H F V F P L C D A R S R T P K P R E L C R D E C E V L E S D L C R Q E Y T I A R S N P L I L M R L Q L P K C E A L P M P E S P D A A N C M R I G I P A E R L G R Y H Q C Y N G S G M D Y R G T A S T T K S G H Q C Q P W A L Q H P H S H H L S S T D F P E L G G G H A Y C R N P G G Q M E G P W C F T Q N K N V R M E L C D V P S C S P R D S S K M G
- Accession
- Q01974
- Protein length
- Fragment
- Predicted molecular weight
- 71 kDa
- Amino acids
- 28 to 403
- Nature
- Recombinant
- Tags
- Avi tag C-Terminus, Fc tag C-Terminus
Specifications
- Form
- Liquid
General info
- Function
Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity). Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PubMed:17717073). In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443).
- Sequence similarities
Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
Storage
- Shipped at conditions
- Dry Ice
- Appropriate short-term storage conditions
- -80°C
- Appropriate long-term storage conditions
- -80°C
- Storage information
- Avoid freeze / thaw cycle, Store in the dark
Notes
Enzymatically biotin-labeled using Avi-tag™ technology
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1 product image
SDS-PAGE - Recombinant Human ROR2 protein (Tagged) (Biotin) (ab271735)
SDS-PAGE analysis of 4 μg ab271735.
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Product protocols
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