Recombinant Human RPL31 protein is a Human Full Length protein, in the 1 to 125 aa range, expressed in Escherichia coli, with >85% purity and suitable for SDS-PAGE, MS.
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Key facts
- Purity
>85% SDS-PAGE
- Expression system
Escherichia coli
- Tags
His tag N-Terminus
- Applications
SDS-PAGE, MS
- Biologically active
No
Amino acid sequence
M G S S H H H H H H S S G L V P R G S H M G S M A P A K K G G E K K K G R S A I N E V V T R E Y T I N I H K R I H G V G F K K R A P R A L K E I R K F A M K E M G T P D V R I D T R L N K A V W A K G I R N V P Y R I R V R L S R K R N E D E D S P N K L Y T L V T Y V P V T T F K N L Q T V N V D E N
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application MS | Reactivity Reacts | Dilution info - | Notes - |
Alternative names
60S ribosomal protein L31, Large ribosomal subunit protein eL31, RPL31
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Recombinant Human RPL31 protein is a Human Full Length protein, in the 1 to 125 aa range, expressed in Escherichia coli, with >85% purity and suitable for SDS-PAGE, MS.
Key facts
- Purity
>85% SDS-PAGE
- Expression system
Escherichia coli
- Tags
His tag N-Terminus
- Applications
SDS-PAGE, MS
- Biologically active
No
- Accession
- P62899-1
- Animal free
No
- Species
Human
- Concentration
- Storage buffer
pH: 8
Constituents: 50% Glycerol (glycerin, glycerine), 1.17% Sodium chloride, 0.32% Tris-HCl buffer, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol
Sequence info
Amino acid sequence
M G S S H H H H H H S S G L V P R G S H M G S M A P A K K G G E K K K G R S A I N E V V T R E Y T I N I H K R I H G V G F K K R A P R A L K E I R K F A M K E M G T P D V R I D T R L N K A V W A K G I R N V P Y R I R V R L S R K R N E D E D S P N K L Y T L V T Y V P V T T F K N L Q T V N V D E N
- Accession
- Protein length
Full Length
- Predicted molecular weight
16.9 kDa
- Amino acids
1 to 125
- Nature
Recombinant
- Tags
His tag N-Terminus
Specifications
- Form
Liquid
- Additional notes
Purified using conventional chromatography techniques
General info
- Sequence similarities
Belongs to the eukaryotic ribosomal protein eL31 family.
Storage
- Shipped at conditions
Blue Ice
- Appropriate short-term storage duration
1-2 weeks
- Appropriate short-term storage conditions
+4°C
- Appropriate long-term storage conditions
-20°C
- Aliquoting information
Upon delivery aliquot
- Storage information
Avoid freeze / thaw cycle
Supplementary info
This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
RPL31 also known as Ribosomal Protein L31 is a component of the 60S subunit of the ribosome. This protein weighs approximately 14 kDa. It plays an important role in protein synthesis within the cell. RPL31 is widely expressed in many tissues including the liver kidney and lung. Its presence in these tissues indicates its importance in cellular function and metabolism.
- Biological function summary
This ribosomal protein facilitates the assembly and stability of ribosomal structures enabling proper translation and protein synthesis. RPL31 is part of the larger ribosomal complex which includes multiple RNA molecules and many ribosomal proteins. It assists in maintaining the integrity of the ribosome during translation which is fundamental for efficient protein synthesis.
- Pathways
RPL31 plays a role in the translation pathway and the ribosome biogenesis pathway. It interacts with other ribosomal proteins such as RPL17 and RPL26. These pathways are critical for cell growth and proliferation. RPL31's function within these pathways highlights its role in assembling ribosomal units and ensuring correct translation and protein production within cells.
- Associated diseases and disorders
RPL31 has been linked to Diamond-Blackfan anemia a rare blood disorder. This connection stems from its role in ribosomal structure and function. Mutations affecting RPL31 or related ribosomal proteins like RPS19 can disrupt normal ribosome biogenesis leading to disorders linked to defective erythropoiesis. Such findings emphasize the importance of RPL31 in maintaining normal cellular and hematopoietic function.
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1 product image
SDS-PAGE - Recombinant Human RPL31 protein (ab176043)
15% SDS-PAGE analysis of ab176043 (3μg).
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