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AB176043

Recombinant Human RPL31 protein

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Recombinant Human RPL31 protein is a Human Full Length protein, in the 1 to 125 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE, Mass Spec.

View Alternative Names

Large ribosomal subunit protein eL31, 60S ribosomal protein L31, RPL31

1 Images
SDS-PAGE - Recombinant Human RPL31 protein (AB176043)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human RPL31 protein (AB176043)

15% SDS-PAGE analysis of ab176043 (3μg).

Key facts

Purity

>85% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

Mass Spec, SDS-PAGE

applications

Biologically active

No

Accession

P62899

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 50% Glycerol (glycerin, glycerine), 1.17% Sodium chloride, 0.32% Tris-HCl buffer, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMAPAKKGGEKKKGRSAINEVVTREYTINIHKRIHGVGFKKRAPRALKEIRKFAMKEMGTPDVRIDTRLNKAVWAKGIRNVPYRIRVRLSRKRNEDEDSPNKLYTLVTYVPVTTFKNLQTVNVDEN","proteinLength":"Full Length","predictedMolecularWeight":"16.9 kDa","actualMolecularWeight":null,"aminoAcidEnd":125,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P62899","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

RPL31 also known as Ribosomal Protein L31 is a component of the 60S subunit of the ribosome. This protein weighs approximately 14 kDa. It plays an important role in protein synthesis within the cell. RPL31 is widely expressed in many tissues including the liver kidney and lung. Its presence in these tissues indicates its importance in cellular function and metabolism.
Biological function summary

This ribosomal protein facilitates the assembly and stability of ribosomal structures enabling proper translation and protein synthesis. RPL31 is part of the larger ribosomal complex which includes multiple RNA molecules and many ribosomal proteins. It assists in maintaining the integrity of the ribosome during translation which is fundamental for efficient protein synthesis.

Pathways

RPL31 plays a role in the translation pathway and the ribosome biogenesis pathway. It interacts with other ribosomal proteins such as RPL17 and RPL26. These pathways are critical for cell growth and proliferation. RPL31's function within these pathways highlights its role in assembling ribosomal units and ensuring correct translation and protein production within cells.

RPL31 has been linked to Diamond-Blackfan anemia a rare blood disorder. This connection stems from its role in ribosomal structure and function. Mutations affecting RPL31 or related ribosomal proteins like RPS19 can disrupt normal ribosome biogenesis leading to disorders linked to defective erythropoiesis. Such findings emphasize the importance of RPL31 in maintaining normal cellular and hematopoietic function.
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Specifications

Form

Liquid

Additional notes

Purified using conventional chromatography techniques

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General info

Function

Component of the large ribosomal subunit (PubMed : 23636399, PubMed : 32669547). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed : 23636399, PubMed : 32669547).

Sequence similarities

Belongs to the eukaryotic ribosomal protein eL31 family.

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Product protocols

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Target data

Component of the large ribosomal subunit (PubMed : 23636399, PubMed : 32669547). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed : 23636399, PubMed : 32669547).
See full target information 60S ribosomal protein L31
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions
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