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AB174424

Recombinant Human RPS4X/SCAR protein

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Recombinant Human RPS4X/SCAR protein is a Human Full Length protein, in the 1 to 263 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE, Mass Spec.

View Alternative Names

CCG2, RPS4, SCAR, RPS4X, 40S ribosomal protein S4, SCR10, Single copy abundant mRNA protein

1 Images
SDS-PAGE - Recombinant Human RPS4X/SCAR protein (AB174424)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human RPS4X/SCAR protein (AB174424)

SDS-PAGE analysis of 3 μg ab174424 on 15% SDS-PAGE gel.

Key facts

Purity

>95% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE, Mass Spec

applications

Biologically active

No

Accession

P62701

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 40% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Product details

This product was previously labelled as RPS4X
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Sequence info

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIDKTGENFRLIYDTKGRFAVHRITPEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG","proteinLength":"Full Length","predictedMolecularWeight":"32 kDa","actualMolecularWeight":null,"aminoAcidEnd":263,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P62701","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

RPS4X also known as SCAR is a ribosomal protein component of the small 40S subunit with a mass of approximately 29 kDa. Widely expressed RPS4X plays an important role in protein synthesis by contributing to ribosome assembly and function. Its presence is detected in various tissues which indicates its significant involvement in cellular protein production necessary for maintenance and survival.
Biological function summary

Proteins that belong to the ribosomal protein family like RPS4X contribute to the formation of the ribosome structure. RPS4X participates in ribosomal assembly as part of the ribonucleoprotein complex. This role is critical for the synthesis of proteins shaping the cellular proteome and maintaining cellular functions. The ability of RPS4X to incorporate into the ribosome ensures that genetic information from mRNA is translated efficiently into the corresponding polypeptide chains.

Pathways

Protein synthesis requires efficient coordination within the translation process where RPS4X functions. RPS4X is involved in the translation machinery alongside other ribosomal proteins and components like RPS6 and eIFs (eukaryotic initiation factors). These interactions are fundamental within the mRNA translation pathways and link RPS4X to processes such as the cell cycle and growth. Ribosomal proteins like RPS4X ensure proper translational control necessary for growth and development.

Proteins such as RPS4X have implications in ribosome-related dysfunctions. Its altered expression or mutation may associate with conditions like Diamond-Blackfan anemia a disorder characterized by defective erythrocyte production. Additionally anomalies in RPS4X are also linked to Turner syndrome where reduced ribosomal activity could play a contributing role. In both disorders there is a potential connection to ribosomal protein RPS19 which is also integral to ribosome function and pathology.
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Specifications

Form

Liquid

Additional notes

ab174424 is purified by using anion-exchange chromatography (DEAE sepharose resin) and gel-filtration chromatography (Sephacryl S-200) with 20mM Tris pH 7.5, 2mM EDTA.

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General info

Function

Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed : 23636399). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed : 34516797).

Sequence similarities

Belongs to the eukaryotic ribosomal protein eS4 family.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed : 23636399). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed : 34516797).
See full target information RPS4X
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions
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