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AB163873

Recombinant Human S100P binding protein (GST tag N-Terminus)

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Recombinant Human S100P binding protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 408 aa range, expressed in Wheat germ, suitable for ELISA, WB.

View Alternative Names

S100PBPR, S100PBP, S100P-binding protein, S100P-binding protein Riken

1 Images
SDS-PAGE - Recombinant Human S100P binding protein (GST tag N-Terminus) (AB163873)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human S100P binding protein (GST tag N-Terminus) (AB163873)

ab163873 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Key facts

Expression system

Wheat germ

Tags

GST tag N-Terminus

Applications

WB, ELISA

applications

Biologically active

No

Accession

Q96BU1

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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Primary Antibodies

AB203689

Anti-S100P binding protein antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-S100P binding protein antibody (AB203689)

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Recombinant Human BS69 protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human BS69 protein (GST tag N-Terminus) (AB161146)

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MMCSRVPSEQSSGTSLLPKDGAPFSWDSLDEDGLDDSLLELSEGEEDDGDVNYTEEEIDALLKEDDPSYEQSSGEDDGGHVEKGERGSQILLDTPREKNSSYSLGPVAETPDLFKLPQLSTSSGHGPAHTKPLNRRSVLEKNLIKVTVAPFNPTVCDALLDKDETDSSKDTEKLSSLGEEMREDGLSPNESKLCTESEGISPNNSAWNGPQLSSSNNNFQQTVSDKNMPDSENPTSVFSRISDHSETPNMELSCRNGGSHKSSCEMRSLVVSTSSNKQDVLNKDSGKMKGHERRLGKVIPVLQTKTRTNVPTFSQSNLEQQKQLYLRSVIAHIEDPEDTNQGISGELCALMDQVHHMQHSKWQHPSDLTTRNYARRQKHLQRYSLTQWVDRNMRSHHRFQRLPDFSYS","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":408,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q96BU1","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The S100P binding protein also called S100PB interacts directly with S100P a member of the S100 family of calcium-binding proteins. This protein has a molecular mass of approximately 40 kDa. It is present in various tissues and organs including the placenta and certain types of epithelial tissues. The protein's expression varies and changes in its expression levels often correlate with different physiological and pathological conditions.
Biological function summary

S100PB modulates the activity of S100P by binding to it which influences several cellular functions. It does not function as a standalone protein but is instead part of complexes that affect cellular signaling proliferation and differentiation. This interaction can impact cellular processes such as cell growth and apoptosis hinting at roles in cellular proliferation mechanisms and stress responses.

Pathways

The S100P binding protein is associated with the regulation of cellular responses to external stressors and intracellular signal transduction pathways. It plays a role in the MAPK/ERK pathway and might influence the activity of proteins like Raf and MEK. These pathways are critical for intracellular communication that controls cell division differentiation and development. The protein interactions and binding activities show its significance within these cellular signaling frameworks.

S100P binding protein involvement has been noted in cancer progression and metastasis as well as inflammatory diseases. In cancer it interacts with and possibly regulates other S100 proteins contributing to processes that facilitate tumor growth and spread. Its role in inflammation may include modulating inflammatory responses linked to the activities of proteins involved in immune regulation. The connection with these disorders makes it a potential target for therapeutic interventions given its influence on cellular signaling and disease-related pathways.
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Specifications

Form

Liquid

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General info

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Product protocols

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Target data

See full target information S100PBP
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Product promise

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